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Health

Dangers of chiropractic treatments under-reported, study finds

May 16, 2012

A woman having a therapeu 008 Dangers of chiropractic treatments under reported, study finds

This article is totally flawed and may I also add that professor Ernst should be ashame of putting out false statements about a professoion that has helped so many people overcome pain. Professor Ernst isn’t the first and definitely not the last to ”sucker punch” the chiropractic profession simply to satisfy their academic journal requirement to the university. My advise to professor Ernst and others who attempt to falsely suggest that chiropractic is dangerous, stay out of  areas you have no business or knowlwdge of writing and focus on your defense when the BCA or ACA decide to make an example of you!

That’s my comment …pass it on…

Dr Anthony

Yepod.com      


poweredbyguardianREV Dangers of chiropractic treatments under reported, study findsThis article titled “Dangers of chiropractic treatments under-reported, study finds” was written by Alok Jha, for The Guardian on Sunday 13th May 2012 23.05 UTC

Chiropractic treatments might appear safer than they actually are because their adverse effects are under-reported in medical trials, a study has found.

Improper reporting of the adverse effects of a medical intervention was unethical, said Edzard Ernst, professor of complementary medicine at the Peninsula medical school, University of Exeter, who led the latest analysis. This had allowed chiropractors to create a falsely positive picture about the safety of their treatments, he said.

Chiropractors use spinal manipulation to treat ailments of the muscles and joints. Some practitioners claim the treatments can be used to treat more general health problems such as colic, asthma and prolonged crying in babies.

In his latest analysis, Ernst’s team collated data from 60 randomised controlled trials (RCTs) of chiropractic carried out from January 2000 to July 2011. They found that 29 of the studies failed to mention any adverse effects of the treatment and, of the 31 trials where adverse effects were reported, 16 reported that none had occurred during the study. The results are published in the April 2012 edition of the New Zealand Medical Journal.

Guidelines for publishing clinical trials require that all adverse outcomes of a medical intervention should be published. If an intervention is totally safe and, therefore has no adverse effects, the researchers should report that there were no adverse effects.

“Imagine you have a drug where mild adverse effects are documented and hopefully rare adverse effects are being reported in case reports,” said Ernst. “Then somebody does a trial on this drug and doesn’t even mention adverse effects. That, in anybody’s book, must be unethical.

“I feel that chiropractors do have a strange attitude towards the safety of their interventions. When you read the literature, you see proclamations that spinal manipulation, according to chiropractors, is 100% safe.”

This is despite hundreds of case studies that have documented problems with the treatment. “About 50% of patients seeing a chiropractor have adverse effects, which is staggering,” said Ernst. “In addition to these fairly mild adverse effects, which basically are pain at the site of manipulation and referred pain sometimes, which only lasts one or two days, we have about 500-700 cases of severe complications being reported.”

With extreme chiropractic movement of the neck, an artery can disintegrate and lead to a stroke, an outcome that is well-documented in medical literature. “We only see what is being published and that can only be the tip of the iceberg,” said Ernst. “Some neurologist sees a stroke and he finds out that this was associated with chiropractic – in 99.9% of cases he won’t publish that.”

Ernst said the under-reporting of adverse effects meant decisions about the best course of treatment for a patient would be made difficult. “Therapeutic decisions ought to be taken not on considering the effectiveness alone but also you have to have effectiveness as a balance with the potential for harm. You have to do a risk-benefit analysis. When you under-report risk, this cannot possibly be done robustly.”

The British Chiropractic Association was approached for a response to the study but a spokesperson said it was unable to comment in time for publication.

 Dangers of chiropractic treatments under reported, study finds

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Dr Dillner’s health dilemmas: what is the normal length of labour?

April 9, 2012

Newborn baby 008 Dr Dillners health dilemmas: what is the normal length of labour?

Perhaps for many of us two hours longer labour pains is not so significant…at least for us males,but it is alerting us to an important fact. We are not as active as we were 50 years ago…leading to significant changes in our physiology. What will be the effect to our biology in another 50 years and what will be the leading cause of dead in the future…due to the lack of exercise? We don’t have to allow our health to succumb to the technological age…get out and get physical!

That’s my comment…pass it on,

Dr Anthony

Yepod.com

 http://www.yepod.com/?p=44371   


poweredbyguardianREV Dr Dillners health dilemmas: what is the normal length of labour?This article titled “Dr Dillner’s health dilemmas: what is the normal length of labour?” was written by Luisa Dillner, for The Guardian on Sunday 8th April 2012 20.00 UTC

Women are taking longer to give birth than they did 50 years ago, according to a paper in the American Journal of Obstetrics and Gynaecology. The research suggests that the length of labour has increased by 2.6 hours for first-time mothers and by two hours for women who have previously given birth. So should you believe this, and does it matter? If you are in labour and your midwife or obstetrician says you have fallen off the Friedman curve (a graph drawn by American obstetrician Emanuel Friedman showing the time it takes in an ideal labour for your cervix to fully open so you can push your baby out), should you admit defeat or wait because labour takes longer these days?

The solution

The first part of labour can take hours. During this time the cervix opens up slowly and painfully to 4cm. From then on the labour is considered “active”, which according to the Friedman curve, means the cervix is meant to open up by at least 1cm an hour.

If the cervix doesn’t progressively open after any two-hour period, then you have fallen off the Friedman curve and could be given oxytocin, a drug that makes contractions stronger and pushes labour along, or even a caesarean section if there are worries about the wellbeing of mother or baby. What this latest research says is that labour is taking longer than when Friedman drew his curve.

It is not completely clear why, because lots of things are different. “Women are older when they give birth, they weigh more and they are less active in labour – they stay in bed more instead of being more ambulatory as they were in the past,” says Katherine Laughon, an obstetrician and author of this latest paper. “It used to take women 3.9 hours to go from a cervix that was 4cm to one that was fully dilated. Now it takes 6.5 hours. Almost all women would give birth within 18.5, now most do so within 24 hours.”

Laughon’s study compared data from about 40,000 women from 1959-66 with data from 98,000 women from 2002-08. Many more women these days have epidurals – which Laughon says increases labour by 40-90 minutes – but since it stops labour hurting, who cares? But this didn’t explain all of the difference. She believes that proper active labour starts later, when the cervix is dilated to 6.5 to 7cm, and that doctors and midwives can wait longer before speeding things up.

In a previous paper, Laughon argued that caesarean section rates may be increasing because doctors leap in too early to diagnose a stalled labour (known medically as failure to progress), before it has even reached its active stage. There is no evidence that waiting is risky to the baby, but that may be because the studies are not large enough to detect a difference as bad outcomes are, thankfully, rare. So it is probably best to wait at least a little longer.

 Dr Dillners health dilemmas: what is the normal length of labour?

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Prostate cancer patients given hope by new ‘triple-whammy’ drug

April 1, 2012

blood tests 008 Prostate cancer patients given hope by new triple whammy drug

Good news for prostate cancer patients…especially for those not responding to present day treatments…research has uncovered another potential drug that can be useful in breathing new life in the battle against cancer. With every ground-breaking news …comes hope of a another day to see the sun-rise…keep fighting and never surrender…

That’s my comment…pass it on..

Dr Anthony

http://www.Yepod.com


poweredbyguardianREV Prostate cancer patients given hope by new triple whammy drugThis article titled “Prostate cancer patients given hope by new ‘triple-whammy’ drug” was written by Robin McKie, science editor, for The Observer on Saturday 31st March 2012 23.06 UTC

A new drug that tackles advanced prostate cancer in three different ways has passed its first hurdle towards being approved.

Scientists reported promising early trial results using galeterone, which is designed to treat cancer that no longer responds to hormone therapy. However, researchers counselled caution as tests on the “triple whammy” drug have been carried out on only a small number of patients.

In their tests, scientists based at Harvard University reported that galeterone reduced levels of prostate specific antigen (PSA), a prostate cancer blood marker, by 30% or more in about half of patients. Eleven patients had PSA reductions of 50% or more, and in some there was significant shrinkage in tumour size.

A total of 49 patients took part in the phase one study, which primarily looked at safety and dosing levels. All had “refractory” or “castration resistant” cancer that had ceased to respond to hormone therapy. Currently there is little doctors can do to help prostate cancer patients who progress to this stage.

Galeterone works in three ways: by blocking “receptor” proteins that respond to testosterone; by reducing the number of receptors in tumours; and by targeting an enzyme that is linked to hormone pathways involved in the cancer. Trial leader Dr Mary-Ellen Taplin described the galeterone study as “exciting for those of us in the medical community treating this life-threatening cancer”.

The findings were presented at the annual meeting of the American Association for Cancer Research in Chicago. A larger phase two trial, focusing on the drug’s effectiveness, is planned later this year.

The results were welcomed by Dr Kate Holmes, head of research at the Prostate Cancer Charity. “This very early stage research, conducted among a small group of men, indicates that galeterone shows potential as a new treatment for men with advanced prostate cancer.

“This new drug is in its infancy and full results have yet to be published, meaning that it is simply too soon to tell whether or not this drug is capable of living up to its early promise.

“Men in the final stages of prostate cancer have very few options available to them and we desperately need to increase the number of effective treatments,” she said.

“The researchers have plans to test the drug in a further trial, to fully investigate the full side-effects and safety of treatment. We look forward to reading the full publication of this study in due course, and await with anticipation the results of further trials.”

 Prostate cancer patients given hope by new triple whammy drug

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A cardiac arrest and a heart attack: what’s the difference?

March 23, 2012

Fabrice Muamba had a card 007 A cardiac arrest and a heart attack: whats the difference?

This a a good article for my students….and everyone esle needing an explanation of how  a cardiac arrest differs from a heart attack. A heart attack is a common result from an unheathy lifestyle due to poor diet and lack of exercise. Cardiac arrest has been more common among atletes who push themselves physically into exhaustion and may have an underlying condition that was never uncovered under medical examination.

That’s my comment ..pass it on,

Dr Anthony

Yepod.com

http://www.yepod.com/?p=40475 


poweredbyguardianREV A cardiac arrest and a heart attack: whats the difference?This article titled “A cardiac arrest and a heart attack: what’s the difference?” was written by Patrick Barkham, for The Guardian on Monday 19th March 2012 20.00 UTC

Fabrice Muamba’s cardiac arrest on the football pitch has become the most visible example of a shocking statistic: at least 12 young people die suddenly every week in the UK because of abnormalities of the heart.

Like Muamba, who is still in a critical condition, many of these tragedies strike during exercise. Phidippides, the Greek messenger who inspired the modern marathon and collapsed after running well over 100 miles in two days, may be the earliest recorded incident of the shocking death of an athlete. But until recently many cardiac arrest fatalities were classified as “natural causes” rather than attributed to a recognisable condition – sudden death syndrome (SDS).

A heart attack is the constriction of blood to the heart muscle caused by blocked arteries, commonly linked to unhealthy lifestyles and old age. A cardiac arrest is totally different and can occur in the young and healthy if the heart goes into a dangerous rhythm, unable to pump blood around the body.

Sanjay Sharma, professor of cardiology at St George’s Hospital in south London, has screened 20,000 athletes since 1994 with the charity Cardiac Risk in the Young (CRY). According to Sharma, an electrocardiogram (recording the rhythm of your heart) and an echo-cardiogram (a sonogram of the heart) can pick up 70% of the conditions that cause SDS in athletes.

It has been reported that 23-year-old Muamba underwent cardiac testing four times in his career. But some serious conditions, such as cardiomyopathies, may be hidden by the natural enlargement of the heart from strenuous exercise. “It can be difficult to be certain where it’s ‘athlete’s heart’ or cardiomyopathy but in an expert setting we are very good at distinguishing between the two,” says Sharma. He would like every young person over 14 who plays sport to be screened. This is expensive but with experts donating their help for free, CRY can perform screenings for £35 per person.

Leicester midfielder Clive Clark was 27 when he suffered a cardiac arrest at half-time in 2007. He recovered, but has never played professionally again. “When a footballer has a cardiac arrest, we would tell them it’s too dangerous to continue playing,” says Sharma. “Not playing football is a small price to give someone back 60 years of life.”

 A cardiac arrest and a heart attack: whats the difference?

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Dr Dillner’s health dilemmas: is it safe to take sleeping pills?

March 11, 2012

Sleeping tablets 007 Dr Dillners health dilemmas: is it safe to take sleeping pills?

Certain medications are essential for some of us to achieve optimal health…for example glucobay and glucophage are medications recommended in controling diabetes. Sleeping pills have all too often been over-prescribed to patients, there are other options in achieving the necessary sleep…changes in eating,exercise,social,and even work can help bring about the rest we need…

That’s my comment…pass it on..

Dr Anthony

Yepod.com

http://www.yepod.com/?p=37910


poweredbyguardianREV Dr Dillners health dilemmas: is it safe to take sleeping pills?This article titled “Dr Dillner’s health dilemmas: is it safe to take sleeping pills?” was written by Luisa Dillner, for The Guardian on Sunday 4th March 2012 21.00 UTC

You have been lying awake for hours, or at least it feels like it. You are desperate for sleep, but it just won’t come. In the medicine cabinet are some sleeping tablets your doctor gave you, but the media has been full of warnings that they aren’t safe. A paper published last week in the journal BMJ Open looked at 10,500 people who had taken sleeping tablets and compared them to similar people who had not taken medication. It found that people who took pills twice a month or more are nearly four times as likely to die early as those who don’t. So should you bin the sleeping pills or take a couple to break the cycle of insomnia? After all, being sleep deprived makes you miserable, knackered and liable to crash the car.

The solution

The research paper showed an association with an increased risk of dying early even for people taking small numbers of sleeping tablets (fewer than 18 pills a year). Taking more than 132 pills a year was associated with increased risks of lymphoma, lung, colon and prostate cancer. However, an association only means that there may be a link – the paper doesn’t prove that sleeping tablets are the cause of people dying earlier. But sleeping pills do have side-effects, such as causing day-time sleepiness and affecting short-term memory.

Even so, some doctors will suggest that you try these medicines to help you break a cycle of insomnia. Taking them for three to five days is usually enough to get back into a habit of sleeping normally. You should not use them routinely because of the risk of addiction. There is also evidence that melatonin (a hormone that controls your body clock) helps you get to sleep and sleep longer, but you will need a prescription for it.

It is easy to get worked up about not sleeping, but often your body will sort it out over a few days. It can be normal to take up to 20 minutes to doze off, so you should be realistic and not get anxious if you don’t drop off immediately. Practice what doctors call “sleep hygiene”, which means avoiding stimulants such as caffeine, nicotine or alcohol in the late evening, or looking at a computer screen before you go to sleep. You should start winding down in the hour before bed and make sure your bedroom is quiet, dark and comfortable.

There is some evidence that cognitive behavioural therapy (CBT), which involves thinking positively instead of fretting about not going to sleep, is effective. There is no good evidence that herbal remedies such as valerian work. Although acupuncture may improve the quality of sleep, it doesn’t help you to nod off.

 Dr Dillners health dilemmas: is it safe to take sleeping pills?

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Autism: how computers can help

February 28, 2012

Gary McKinnon with his mo 005 Autism: how computers can help

A lot of the articles on autism is pretty much on the disadvantages and problems faced by those who are diagnosed with it. But there is some good news for those who have mild autism, especially individuals with skills that fall into the IT industry. New research suggests that the traits of autism can be found more frequently in people involved with computers.  So I am left comtemplating whether or not I possess the traits of autism myself?

http://www.yepod.com/?p=35881

That’s my comment…pass it on,

Dr Anthony

Yepod.com

logo smaller with star Autism: how computers can help 


poweredbyguardianREV Autism: how computers can helpThis article titled “Autism: how computers can help” was written by Giulia Rhodes, for The Guardian on Sunday 26th February 2012 20.00 UTC

In 2001, the technology magazine Wired coined the phrase “geek syndrome” to describe the threefold increase in autism diagnoses in California’s Silicon Valley over the space of a decade.

The rumour that Bill Gates himself, founder of Microsoft and figurehead of the world IT industry, displays the traits of Asperger’s syndrome, the high-functioning form of autism, spread like wildfire, across – appropriately – the internet.

More than a decade later Cambridge University’s Autism Research Centre is now running a study investigating the previously established link between parents working in hi-tech, scientific and mathematical industries and an increased incidence of children on the autism spectrum. The National Autistic Society reports in its latest member’s magazine that the number of software packages and apps designed specifically for people with autism is rocketing. IT companies in the UK and beyond are actively recruiting an autistic workforce for its highly technical and concentration skills.

The relationship between computers and autism is undisputed – and double-edged. Many autism experts agree with Temple Grandin, an author and professor at Colorado State University, herself autistic, who believes that without “the gifts of autism” there would probably be no Nasa or IT industry. Yet the high-profile cases of Gary McKinnon and Ryan Cleary, both of whom have Asperger’s syndrome, are just two examples of how that relationship can go wrong.

Last November a conference organised by Research Autism considered this apparent contradiction, asking are computers a blessing or a curse for people with autism? Richard Mills, director of research at the charity and chair of the conference, believes the answer is complicated: “The computer age totally changes the world of autism. Things are instant, and they are unregulated. We see tremendous advantages to this if it is properly managed – and huge pitfalls if it isn’t.”

The risks are not just for the small proportion who hit the headlines though. “We have so many parents concerned about their children’s computer use, and about the explosion of packages designed to help people with autism to communicate, which have not been properly evaluated. We must proceed with rather more caution and try to think through problems before they actually happen.”

The potential of computers to help a group that struggles to communicate and form relationships in real life is obvious. Professor Simon Baron Cohen, Director of the Autism Research Centre believes they outweigh the possible risks: “We can use computers to teach emotion recognition and to simplify communication by stripping out facial and vocal emotional expressions and slowing it down using email instead of face-to-face real-time modes.”

Research at Nottingham University and Carnegie Mellon University in Pittsburgh has found that people with autism value the increased control over their interactions that is afforded by the filter of a computer screen. They can observe interactions, choose when to be sociable and make contact with other people who have autism.

Presenting information visually in the precise and predictable computer format suits the autistic mind, says Baron Cohen, and can provide “a tool or platform for developing further skills”.

He also identifies the role of computers in making geeks fashionable: “The new technology is chic, so people who are talented at using technology acquire a certain kudos, thereby further reducing any stigma that is often associated with disability.”

One risk though is that the computer can itself become an obsession which, in extreme cases, leads the user into serious problems. The reports of Essex teenager Ryan Cleary, charged with a cyber-attack on the Serious Organised Crime Agency, leaving his computer only to use the bathroom, may be extreme but they are far from unique, says Mills: “We do need to think about the tendency in autism to become fixated on narrow activities. They may have the skills to use computers but not to know when to stop.”

In March it will be 10 years since Gary McKinnon’s arrest for allegedly hacking into a number of US military computers. High court judges last month set a July deadline for the home secretary to decide whether McKinnon will be extradited to face trial and a possible 60-year sentence. His mother, Janis Sharpe, is well aware of the dichotomy of computer use and autism. “When Gary was nine, we bought a primitive Atari,” she says. “He would beg me not to send him out to play so he could use it. We wanted him to mix more but we didn’t want to deny him the information, pleasure and security computers gave him. They were an outlet for him to be himself, and that boosted his self-esteem.”

She recalls accompanying her by-then-adult son to a Christmas party at the family home of a girlfriend. “Gary got his computer out. I told him he couldn’t use it at a party but he couldn’t understand.”

The relationship foundered, and McKinnon retreated further into his virtual world. “People with autism need space, and computers can offer that,” says Sharpe. “But we have to make sure they don’t take over and make other relationships, already difficult for people with autism, even harder.”

She advises parents to keep computers in communal spaces, limit their use and to help children learn to question what they read, guidelines which Mills supports. “This virtual world has to help people access the real world, not isolate them further. They must control it, not be controlled by it,” he says. “We have to reinforce the positives.”

For further information see researchautism.net and autism.org.uk

 

 Autism: how computers can help

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How the world fell in love with quick-fix weight loss

February 25, 2012

Diet tube 007 How the world fell in love with quick fix weight loss

There are many individuals who have tried all sorts of quick weight loss programs with poor results. In the end…many have turned to plastic surgery to attain the body they have always hoped for. Perhaps we are too impatient to shed the weight over the next 12 months…remember it has taken years to gain the weight…so it can take some time to take it off. Good old fashion calorie control and exercise is the best way to go. Tried not to succumb to the temptation of diet pills,quick weight loss fads,and plastic surgery. Slow and steady…you can reach your desire weight…

That’s my comment..pass it on

Dr Anthony

Yepod.com

http://www.yepod.com/?p=35321    


poweredbyguardianREV How the world fell in love with quick fix weight lossThis article titled “How the world fell in love with quick-fix weight loss” was written by Amanda Mitchison, for The Guardian on Friday 24th February 2012 23.00 UTC

Ginevra Tamberi, a 21-year-old film studies student from Rome, has very tall, very skinny parents. Her brother can eat 4,000 calories a day and remains one of nature’s giraffes. But Ginevra is not so lucky. She eats one slice of bread and it goes down her throat and directly on to her bum.

Ginevra tried everything: the Aktins diet, the Dukan diet, the Scarsdale diet, the Zone diet, the cabbage diet, the onion diet. She saw a private nutritionist and a personal trainer. All to no avail.

In desperation she visited the plastic surgeon Marco Gasparotti. Ginevra says, “Everybody in Rome knows Gasparotti.” And everybody does, too: you cannot throw a brick in Italy and not hit Dr Gasparotti demonstrating his innovative techniques on some TV chat show. For Gasparotti is no slouch; he has a liposuction cannula to his name and has patented an elastocompressive cellulite-busting girdle called the Lipo Contour Elite Capri. He has also garnered countless international awards, and is at the very forefront of innovative ways of redraping skin and sucking out and resculpting fat that cannot be described to readers looking at this magazine over breakfast.

Ginevra went to Gasparotti for liposuction. She wanted, as it were, to be vacuumed down a couple of dresses sizes. But Gasparotti was not encouraging – liposuction, he said, was for improving shape and contour, not for comprehensive fat removal. Instead, Gasparotti had another, better trick up his sleeve: his new Diet Tube. A week later, after some medical tests, Ginevra returned to Gasparotti’s clinic and she came out with a piece of plastic tubing sticking out of her nose. One end of the tube went down into her stomach, the other was attached to a small electric pump.

For 10 days Ginevra wore the nasogastric tube. She ate nothing and the pump, working day and night, sent tiny amounts of a protein-filled liquid into her stomach to stave off hunger. The tube, she says, didn’t restrict her lifestyle. When she went out, she just popped the pump into her Prada bag and nobody in the street seemed to notice she had a tube up her nose. I find this surprising. Normally you notice when people have tubes up their noses, just as you also notice when they are wearing gas masks. But Rome is Rome.

On Diet Tube Ginevra experienced occasional moments of lassitude, but mostly she felt great. She says, “It was purifying everything. My skin was, like, unbelievable. It was so clean, so pure, like a baby’s. Amazing!” Ginevra grew used to the faint buzzing of the pump, and didn’t feel nauseous or hungry. But she did miss chewing. “So I was just having tea – green tea – all the time.”

Didn’t she get sick of the tea?

“If I see green tea now, I am going to die.”

And what did her friends think?

“They’re used to my strange stuff, my weird things.” And anything was better than the onion diet.

By the end of the 10 days, Ginevra had lost 7kg. She gave Diet Tube a break. Six months later, she had another go and lost a further 5kg. She is now a size 14, not a size 16–18. Her friends and family have also tried it. Ginevra’s aunt, another of the family’s non-giraffes, has lost 30kg. “My aunt is so happy, she could live on Diet Tube. I saw her with it and she was feeling so powerful. She was really putting herself into her cooking, making lasagne and parmigiana and polpettone and Mont Blanc.”

Last year, 1,500 patients underwent Diet Tube. Numbers are escalating – there are now eight Diet Tube clinics in Italy, centres in Barcelona, Athens and Madrid, and franchise negotiations underway for a dozen other countries, including the UK. The fact that such an outlandish procedure can flourish is hardly surprising. As a nation we are getting fatter and fatter. We are also watching too many makeover TV programmes and becoming increasingly susceptible to the idea of the quick fix. Ten Years Younger, and Extreme Makeover have a lot to answer for. Invasive beauty procedures have been normalised and there are so very many to chose from : face-lifts, eye tucks, tooth whitening, Botox, liposuction, laser, chemical peels, silicone injections, collagen red light therapy… By the time you are 50, you no longer have the face you deserve, but the face you can pay for.

The same holds true for waistlines. If, for whatever reason, you are not up to dieting or spending time in the gym, there are other short cuts. You can experiment with hypnotherapy or with algae or with Peter Foster’s spooky remedies. Or you can resort to non foods: egg white omelette, zero calorie jelly, oat bran, the abominable Dukan pancake. Or, you can take a very big breath, brace yourself and go for weight loss (or “bariatric”) surgery.

Here are the main options: gastric band, gastric balloon, gastric bypass and the relatively new gastric sleeve. I looked up my local weight-loss surgeons, the eminently respectable Bariatric Group. Their website goes into painful detail. The least invasive procedure is the gastric balloon, which fills up the patient’s stomach and gives them a feeling of fullness. The procedure is done under sedation: a silicone balloon is inserted endoscopically into the stomach and then filled up with blue saline solution. Why blue saline? Just in case the balloon bursts and starts to travel down and block up the intestines. The video voiceover says, “So if you do have a puncture and you start peeing green, then you know there’s a problem.” You bet.

The balloon is only temporary – it has to come out after six months. All the other options are permanent (though the band is reversible) and require a general anaesthetic. They all involve reducing the capacity of the stomach to a lesser or greater extent. The most extreme option is the gastric bypass, in which a section of the top of the stomach is stapled off to create a little pouch that is then attached directly to the intestine. The diagrams show just how radical this surgery is: all that the patient can use is a tiny pocket of stomach, and the now redundant, bypassed stomach and a tail of intestine are left lying there in the abdominal cavity like a dead puppy.

A gastric bypass is a major, make or break operation. Most patients are hugely fat and unfit, and 0.2% of them will die during or as a result of the operation. But the most common bariatric procedure in the UK is the gastric band, which involves an inflatable silicone ring being placed around the top of the stomach, thus reducing how much the patient can eat. The ring is connected to a filling port by a thin tube, so the band can be tightened or loosened by adding or reducing the fluid in the port.

A number of celebrities have had gastric bands: Fern Britton, Anne Diamond, Vanessa Feltz, Sharon Osbourne. But many normal mortals have also had the operation. Hollie Rogers, 23, had a gastric band fitted privately by the Bariatric Group when she was 19 and weighed 17 and a half stone (111kg). Her mum paid – nobody else knew how miserable being fat was making her.

The surgery, according to Hollie, was not a big deal. She had a pre-op diet, then one night in hospital for the operation itself and then a series of follow-up appointments at which they gradually filled up the port and tightened the band. Three years on, she has a one inch scar that “has pretty much faded.” What’s more, she is rather pleasingly bionic – with a slightly knobbly bit “underneath my boobs and above the middle of my belly button” where the port lies.

Thanks to the band, she has lost six and a half stone (41kg). The band, she says, “forces you to change your eating habits. It forces you to eat less.” In the old days, she’d have had her dinner and a couple of hours later would settle down to a takeaway or a bag of chips. Not now. “I eat the same amount as anyone who is eating healthily. And I can eat most things, except steak and bread. I mean, I can have one slice of bread, but not eight rounds of toast, which is what I did when I was overweight.”

She has never regretted the operation. She says, “I’m so glad I didn’t wait. In your 20s you want to go out and have fun. Before, I always felt I’d stand out for the wrong reason.” Hollie has released her first album. Recently, she went on a snowboarding holiday. She is having fun.

Thinnies can never know the misery and frustration suffered by the very overweight. It is a hellish cycle to be stuck in: the more you eat, the larger and hungrier you get. The larger you get, the harder it is to move and the more humiliating it is to put on a swimming costume. So you settle back and eat more. Eventually you reach the catastrophic tipping point: you are too large to exercise or even get up and down the stairs easily, and the biochemical regulatory systems in your body (the naturally released enzymes that suppress appetite) stop working properly. Now you are never sated. All you want to do is eat, eat, eat.

At this juncture, losing even as much as a stone (6.3kg) won’t do much. To make any appreciable difference to your health outcome – to reverse your type 2 diabetes, and get you off your blood pressure tablets and give your knees a rest and lower your cholesterol, you have to lose seven or nine or even 15 stone. For that, you will need to spend a very long time on a very low-calorie diet, and have the willpower of a Latin American despot.

Technically there is no reason why someone who is very heavy – 20 or 22 stone, say – should not be able to lose weight. But the surgeons think otherwise. Richard Welbourn, the clinical director of the Bariatric Group, calculates the answer thus: “If you have a Body Mass Index (a measurement based on an individual’s height and weight. A healthy BMI is anywhere between 18.5 and 24.9.) of 40 and you are seven stone overweight, it would be like walking across the Atlantic and running five marathons. That is the straight calorie equation. And running marathons makes you hungry.”

Meanwhile, Alberic Fiennes, president of the British Obesity and Metabolic Surgery Society, says, “If you have a BMI of 40-something, and you’ve been that way for several years, it is overwhelmingly likely to be irreversible – whatever the thin people think.”

Eating, Fiennes says, is in part an involuntary process: “It’d be like asking someone to hold their breath for 15 minutes. Most people can do it for one minute, or two minutes, or maybe four minutes if they’ve been doing diving practice. But 15 minutes? You can’t. You have to breathe. And when you breathe, you gasp.”

“There is a moral stigma to obesity,” continues Fiennes. “These people are seen as weak, and stupid and greedy. But obesity is a disease.”

Fiennes believes it is outrageous that we aren’t carrying out more bariatric surgery. There is, it seems, a postcode lottery with many primary care trusts and commissioning groups refusing or hugely restricting access. Last year, around 4,000 bariatric operations were carried out on the NHS. Yet, according to the guidelines set out by Nice (The National Institute for Health and Clinical Excellence), adults with a BMI of 40 or over (or a BMI of 35 with co-morbidities) should be considered for surgery. That means – shut your eyes for a minute before reading this frightening figure – 1.2 million people in the UK are eligible. We really are becoming a nation of whales.

There is no doubt that bariatric surgery, when carried out with the right medical and psychological pre- and post-operative care, can be hugely beneficial. It prevents premature death, vastly improves quality of life and is very cost-effective for the NHS (a recent study showed that 85% of severely obese patients with diabetes no longer suffered from the disease two years on from surgery). Dr David Haslam, a GP and the chair of the National Obesity Forum, says “I’ve seen hundreds and hundreds of people’s lives transformed by bariatric surgery. It is positively life-saving.”

Nevertheless, bariatric surgery should be treated with extreme caution – as should any operation that entails removing or drastically curtailing a vital organ of the body. And while surgery opens some doors, it also sometimes seems to close others. A very low calorie diet maintained over months or even years is going to be a painful and uphill road, impossible to keep to without enormous amounts of moral support. But why would anyone – patient or health carer – persevere on such a programme when a permanent surgical remedy is available?

Take the case of Justine, a 49-year-old journalist who weighs over 20 stone (127kg). She has had weight problems since the age of four, when her teenage mother first put her on a diet. Two years ago she went to her local GP surgery to join up with Counterweight, an NHS-funded diet programme that provides one-to-one support to people wanting to lose weight.

This is Justine’s story: “The nurse said, ‘I can’t see you – you are too heavy for Counterweight.’ She told me that if you are over a certain weight or BMI, they send you to hospital. So, I went to my local hospital – it was a very strange meeting. I went along to see the doctor for what I thought was a meeting about Counterweight. He said, ‘What we find is that people of your age and weight find it impossible to keep the weight off. The only answer is surgery.’

I said, ‘That seems a bit radical. Do you have any other solutions?’

He said, ‘Well, not really, but would you like to see the dietician?’

“About seven and a half months later, I finally get the meeting with the dietician and I get on the scales and she was talking about surgery. And I said, ‘Is there no other option?’

She was very surprised. She said everybody wanted it – they were biting her hand off to get surgery. And I was apparently a good contender. Surgery: that was all they were interested in.”

So she went along to have her hand held, and all they wanted to do was cut her open?

“Yeah,” she says bleakly. “Something like that.”

There is a madness in our mindset about food. How can we have got so fat? How can we have failed so dismally to get so many people to eat properly? A lot of work on healthy eating is already done in schools and in GP surgeries, but the message isn’t getting home. How can it when food that is bad for you is so much cheaper, crunchier and more convenient?

Hopefully one day, when we have banned crisps and all orange breadcrumbed food, we will look back on today as the Dark Age Of Obesity. Maybe by then we will also have finally developed a safe appetite-suppressant drug and bariatric surgery will all but disappear. There is a precedent for this – when the drug cimetidine became available in the late 1970s, patients stopped being routinely given gastrectomies for gastric ulcers.

In the meantime, desperate patients can always travel to Rome for their nasogastric tube. Over a crackly telephone line I ask Dr Gasparotti about the Diet Tube diet. “It’s not a diet,” he says quickly. “It’s wrong to call it a diet. It is a nutritional protocol. A very strong motivational therapy.”

What’s so wrong with diets?

“Diets take too long. You say to these people, ‘It is very important, so keep to this diet and come back and see me in three or four months.’ They can’t do it. They go out to supper with a friend. They eat. But I say to them, ‘Give me 10 days of your life, OK? In 10 days you will have lost between 8% and 10% of your body weight. Don’t worry. You will get thinner. It is mathematical! It’s biochemical, OK?’”

OK.

“So it’s a fast – but with proteins. And as there are proteins, you don’t lose any muscle. You will eat nothing because you won’t be hungry. You won’t have any inconvenience. You can carry on working. You can have a shower, you can go swimming. We don’t recommend going to the gym for the first week, but these people don’t go to the gym anyway. And…” He pauses before the punchline: “You slim while you sleep!”

Gasparotti explains that Diet Tube was originally devised for the very overweight – for “enormous obese people who couldn’t even move”. He says, “We don’t just give it to anyone. You have to be over 18 and in good health. If I began to give it to girls who just wanted to lose two or three kilos, they’d shoot me!”

But a minute later he adds, “Understand. It is obvious. I have to say that in rare cases…” – at this point I can almost hear him rolling his eyes – “unmotivated people who aren’t able to move around much and are very lazy and want to lose eight or nine kilos. Well, of course one can do it for them, too.”

So if I get on a bus in Rome, will I see people with tubes in their noses? “It’s become a pretty common thing now. You see lots of lawyers and businessmen going about the city with their tubes and their briefcases.”

Isn’t that a bit extreme?

“Look,” he says darkly, “our life today is very neurotic, very fast. Nobody looks after themselves.”

Has he tried Diet Tube himself?

“Yes! Stavo benissimo. I felt happier. It was euphoric making.”

Like a medieval saint on a fast?

“Well, yes! Once, there was a week of fasting at Lent. And you only ate fish on Fridays. That’s all gone now.”

 

 How the world fell in love with quick fix weight loss

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Dr Dillner’s health dilemmas: should I use moisturiser?

February 13, 2012

Cream pot 008 Dr Dillners health dilemmas: should I use moisturiser?

Why not? I think using a moisturiser is a good idea for both men and women. You face gets hit daily by the sun,wind,pollution….just about everything imaginable comes into contact with your face…even your boss tries to get in some face time…yeah talk to the hand buddy…so you need to give your face a little love and tenderness…a good washing and a moisturiser done nightly before bed-time will do…

That’s my comment …pass it on…

Dr Anthony

Yepod.com

http://www.yepod.com/?p=32981    


poweredbyguardianREV Dr Dillners health dilemmas: should I use moisturiser?This article titled “Dr Dillner’s health dilemmas: should I use moisturiser?” was written by Luisa Dillner, for The Guardian on Sunday 12th February 2012 20.59 UTC

There’s so much hype around moisturisers that you have to wonder how good they really are. How can a potion revive skin that has been battered by cold winds and dried up from the central heating? As we get older our skin becomes more dry and wrinkly. So can a moisturiser rid your skin of the fine lines of ageing and plump it up to its teenage glory days? And does an expensive jar of exclusive cream do anything more than a cheap pot from the supermarket?

The solution

Moisturisers contain humectants (eg glycerine) that attract water and keep it in the skin. They also contain emollients and are usually blended with oils then emulsified into a cream, which acts as a barrier against external irritants.

Between the cells in the outer layer of skin are sebum and lipids that give the skin its fresh, plump look. As we get older we lose these and our skin looks dull and dry. Moisturisers, by rehydrating the skin, refill the cell space.

“By attracting water back into the epidermis your skin transmits light differently,” says Dr Jane McGregor, a consultant dermatologist at Barts and the London NHS Trust. “It will feel better, the texture of your skin will be improved and it will not be so dry or itchy. But you don’t need to buy expensive creams, a simple aqueous cream will do.” Soap, says McGregor, dries skin out, which is why most dermatologists don’t use it. Even water can cause chapping.

Simple moisturisers stay in the epidermis; they don’t regenerate cells or get rid of fine lines. But some more expensive products claim to do both. Retinoids were originally used to treat acne but have now been incorporated into cosmetic creams. “The exact way in which retinoids work is not fully understood,” says Dr Bav Shergill, spokesman for the British Association of Dermatologists. “There is some evidence to support their role in stimulating the production of collagen in the dermis, which may plump out fine lines. They also seem to increase the cell turnover in your skin, which smoothes the appearance of skin by exfoliation and improving skin tone. Retinoids are essentially a vitamin A derivative and in terms of concentration a dermatologist would prescribe something that was 0.025% concentrate.” This is considerably higher, says Shergill than the amount in cosmetic creams. “Retinoids do have their downsides – they can make skin red, sore, flaky and irritated.” They can also make your skin more sensitive to UV light and effects vary between people.

There are so many skin creams that make extravagant claims but few research papers to support them. As your skin continues to flake in this cold snap all you need is a cheap tub of moisturiser to make it glow again.

 Dr Dillners health dilemmas: should I use moisturiser?

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Why I’m off for some vitamin D – until the sun comes out

February 7, 2012

sun 007 Why Im off for some vitamin D – until the sun comes out

There’s has always been discussion on the pros and cons of vitamin supplementation in our diets. I see no harm in taking vitamin D and other supplements as long one stays within the normal dosage recommedated by physicians and FDA guidelines. Usually common sense dictates following the instructions listed on the bottle or physician’s orders. Never decide to begin ingesting supplements until your have discussed doing so with your family doctor first.  Vitamin D is an important vitamin from strong bones,growth, and for many chemical reactions that occur within our bodies. Moderation is the key to absorbing sufficient Vitamin D. As for sunshine….be careful not be burn ..wear sunscreen protection…

http://www.yepod.com/?p=31666

That’s my comment…pass it on…

Dr Anthony


poweredbyguardianREV Why Im off for some vitamin D – until the sun comes outThis article titled “Why I’m off for some vitamin D – until the sun comes out” was written by Ann Robinson, for guardian.co.uk on Thursday 26th January 2012 18.14 UTC

Vitamin D is in the news again, and while the experts squabble over it, I’m off to buy myself some supplements. The chief medical officer for England has told GPs like me to advise those at risk to take supplements. And since half the adult population of the UK is lacking vitamin D in the winter months and deficiency is being linked to a growing list of health problems, I can’t see a good reason not to take a small multivitamin a day – at least until the sun comes out. I’ll stick to the recommended daily amount as you can have too much of a good thing, even vitamins.

Vitamin D is essential for bone growth and health, and deficiency can cause rickets in the young and a condition called chondromalacia in adults. You wouldn’t think rickets still existed in the UK but it probably never went away and is increasingly recognised as a cause of fractures in susceptible children.

Recently two parents, Rohan Wray and Chana al-Alas, were accused of murdering their four-month-old baby who died two years ago from sudden infant death syndrome (Sids, also known as cot death). The baby, Jayden, was found to have multiple injuries and the parents were accused of shaking the baby to death. But pathologist Dr Irene Scheimberg, based at Royal London Hospital, found evidence of rickets in Jayden at postmortem and the judge directed the jury to acquit.

Since that tragic case, Scheimberg says she has discovered vitamin D deficiency in eight further cases of Sids and in 30 cases of children who have died of various causes and had postmortems. A colleague of hers, Dr Marta Cohen, working in Yorkshire has also found vitamin D deficiency in 18 out of 24 cases of Sids and in 45 babies under the age of one, who died of other causes. Both doctors are calling for further investigation into the implications of vitamin D deficiency and highlighting the need to be aware of rickets in cases of Sids, which can be mistaken for non-accidental injury.

This adds weight to those calling for widespread vitamin D supplementation in the UK. Advice from the chief medical officer for England, Sally Davies, was for at-risk groups – which includes pregnant and breastfeeding women, children aged six months to five years old, people aged 65 or over, people who are not exposed to much sun (the housebound, those who cover up their skin for cultural reasons and people who have darker skin, whose bodies are unable to produce vitamin D as easily) – to take vitamin D. But there have been calls to introduce supplements for all the population in Scotland, because of high levels of multiple sclerosis which may be linked to vitamin D deficiency. Ryan McLaughlin, 13, launched a campaign, Shine on Scotland, in response to his mother’s diagnosis of MS, while Professor George Ebers of the Nuffield department of clinical neurosciences at Oxford University believes the evidence is now good enough to justify dosing the entire population with vitamin D. Professor George Ebers of the Nuffield Department of Clinical Neurosciences at Oxford University is quoted, saying that he believes the evidence is now good enough to justify dosing the entire population with vitamin D. Last month, his team published evidence of a link between MS and an inherited tendency that leads to vitamin D deficiency.

Scotland’s chief medical officer, however, Sir Harry Burns, says in the same article he thinks there needs to be “broader scientific consensus” before change is considered. He warns that dietary supplements can cause harm and that we need to wait for good randomised studies in large populations. He wants to wait for the conclusions of a review of the evidence by the UK government’s scientific advisory committee on nutrition in 2014.

But Ebers says that is too long. He reflects that there was evidence to support recommending folic acid supplementation for all pregnant women to prevent problems like spina bifida, many years before the public health authorities backed it.

Bruce Hollis, professor of paediatrics and biochemistry at the Medical University of South Carolina, agrees, insisting there’s no point waiting for a large randomised trial because it’s unlikely to ever happen. He says it would be hard to attract funding for an expensive, large scale trial as drug companies would be unlikely to make a profit on cheap vitamin supplements.

The best source of vitamin D is sunlight on the skin. Vitamin D is also found in a small number of foods (oily fish, eggs, cheese and meat) but it is difficult to get enough vitamin D from diet alone. In the UK, all margarines and infant formula milks are already fortified with vitamin D and it is also added, in small amounts, to other foods such as breakfast cereals, soya and some dairy products,. Breastfeeding mothers need adequate vitamin D levels of their own to ensure their babies get enough.

You can buy single vitamin D supplements at most pharmacies and supermarkets. Pregnant women who take vitamin D as part of a multivitamin should avoid supplements containing vitamin A (retinol), which can be harmful in pregnancy.

While the experts continue to debate, we may all be well advised to take a daily vitamin D supplement and expose our skin to whatever weak winter sunshine we can.

 Why Im off for some vitamin D – until the sun comes out

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Fighting malaria with one hand tied back

February 3, 2012

Mosquitos on a net 007 Fighting malaria with one hand tied back

It’s more often than not that mortality figures are under-estimated or lower than reported…are you really surprise? Malaria is a serious disease…  No matter how strong you may think you are…your immunity to malaria may not be enough to succumb to the disease. How long will the insecticides to effective in keeping the populations of mosquitoes at bay?….well until they develop a resistance to the chemicals we are using…..there’s got to be a more natural approach in curbing the over-population of these blood sucking critters..! Any ideas out there…share it with us…

http://www.yepod.com/?p=31177

Pass it on,

Dr Anthony

Yepod.com  


poweredbyguardianREV Fighting malaria with one hand tied backThis article titled “Fighting malaria with one hand tied back” was written by Sarah Boseley, health editor, for The Guardian on Friday 3rd February 2012 06.29 UTC

Decades of assumptions about the lethality of malaria have been overturned by the publication of a paper in the Lancet from an academic institute in Seattle which says the disease kills twice as many as everybody thought. Even more extraordinary – it would seem that conventional wisdom about the disease has been wrong all this time.

It does not just kill babies and children under five — it kills adults too, in nearly as large proportions.

The Institute of Health Metrics and Evaluation has astounded the global health community by claiming it has been fighting malaria apparently with one hand behind its back. The death toll has come down since 2004, thanks to huge efforts to get insecticide-impregnated bednets to households and treat those who are sick with better drugs, but all the while an older age group has been neglected.

“These are certainly results which surprised us when we first did the analysis,” said Steve Lim, one of the authors of the Lancet paper. “It is new to what is taught in public health and medical school, which is that when kids are exposed to malaria at a very young age, it conveys immunity.”

Only last year the World Malaria Report gave mortality figures which are half those the institute has found – 655,000 deaths compared to 1.2 million. It is an extraordinary gulf and there will be lots of debate about the statistical methods used by the Seattle team.

But the institute has form. This is part of a five-year project, funded by the Bill and Melinda Gates Foundation, to obtain the best possible data for the toll of death and disease from vario

How to tell if your olive oil is the real thing

January 10, 2012

VIRGIN OLIVE OIL FACTORY  007 How to tell if your olive oil is the real thing

My friend Donika Llace, a medical office administrator in Chicago is always telling me about the benefits of olive oil, She claims to taking two tablespoons of olive oil daily as a supplement to her regular daily diet. In fact, she is not alone in thinking that the benefits of olive oil go far beyond the kitchen. Many in Europe, as in Italy and Albania feel that olive oil can prevent cardiovascular disease,constipation,arthritis, or  many  of  the common ailments experience by patients. So why not give it a try? It’s a natural approach to natural living…Donika Llace suggests “talking to your family physician before taking any supplements”.

Pass it on,

Dr Anthony         


poweredbyguardianREV How to tell if your olive oil is the real thingThis article titled “How to tell if your olive oil is the real thing” was written by Jon Henley, for The Guardian on Wednesday 4th January 2012 19.59 UTC

Last month, the Olive Oil Times reported that two Spanish businessmen had been sentenced to two years in prison in Cordoba for selling hundreds of thousands of litres of supposedly extra virgin olive oil that was, in fact, a mixture of 70-80% sunflower oil and 20-30% olive.

In 2008, Italian police arrested over 60 people and closed more than 90 farms and processing plants across the south after uncovering substandard, non-Italian olive oil being passed off as Italian extra virgin, and chlorophyll and beta-carotene being added to sunflower and soybean oil with the same aim.

Most alarmingly, a study last year by researchers at the University of California, Davis and the Australian Oils Research Laboratory concluded that as much as 69% of imported European olive oil (and a far smaller proportion of native Californian) sold as extra virgin in the delicatessens and grocery stores on the US west coast wasn’t what it claimed to be.

In Britain, of course, it wasn’t so very long ago that the most likely place to find olive oil was the chemist. Today, thanks partly to the health claims made on its behalf and partly to the fact it tastes good, the oil Homer called “liquid gold” is in half of all UK homes and we get through 30m litres of olive oil every year – more than double than we did decade ago. We’re now, in fact, the world’s 10th biggest olive oil-consuming nation. So with a litre of supermarket extra virgin costing up to £4, and connoisseurs willing to pay 10 times that sum for a far smaller bottle of seasonal, first cold stone pressed, single estate, artisan-milled oil from Italy or Greece, can we be sure of getting what we’re paying for?

The answer, according to Tom Mueller in a book out this month, is very often not. In Extra Virginity: the Sublime and Scandalous World of Olive Oil, Mueller, an American who lives in Italy, lays bare the workings of an industry prey, he argues, to hi-tech, industrial-scale fraud. The problem, he says, is that good olive oil is difficult, time-consuming and expensive to make, but easy, quick and cheap to doctor.

Most commonly, it seems, extra virgin oil is mixed with a lower grade olive oil, often not from the same country. Sometimes, another vegetable oil such as colza or canola is used. The resulting blend is then chemically coloured, flavoured and deodorised, and sold as extra-virgin to a producer. Almost any brand can, in theory, be susceptible: major names such as Bertolli (owned by Unilever) have found themselves in court having to argue, successfully in this instance, that they had themselves been defrauded by their supplier.

Meanwhile, the chemical tests that should by law be performed by exporters of extra virgin oil before it can be labelled and sold as such can often fail to detect adulterated oil, particularly when it has been mixed with products such as deodorised, lower-grade olive oil in a sophisticated modern refinery. Nor do national food authorities appear particularly bothered as long as the oil isn’t actively harmful, which is rare. In Britain, says Judy Ridgeway, one of the UK’s leading olive oil experts, the Food Standards Agency has not done any checks on olive oil in five or six years. “And it only does chemical tests, not taste tests,” she adds.

The EU now also requires extra virgin oil to pass assorted taste and aroma tests, assessed by panels of experts: the oil has to be suitably fruity, bitter and peppery, and cannot display any of 16 different defects, including “grubbiness”, “mustiness” and “fustiness”. But bad stuff still gets through.

Ridgeway says it is “hard to say what percentage of faulty oil gets through” to Britain. “It will vary seasonally – there will be more at this time of year than in March or April, but it’s appreciable. They buy in good faith, but there are faulty oils on our supermarket shelves, without any argument.”

The olive, in more than 700 varieties or cultivars, has been grown for its oil in the Mediterranean since 3000 BC. Unlike most vegetable oils, which are extracted from seeds or nuts, good olive oil is made using a basic hydraulic press, or more modern centrifuge, so it is more a fruit juice than an industrial fat. It comes in several qualities, including lampante, or “lamp oil”, which is made from damaged or ground-gathered fruit and cannot be sold as food; virgin; and extra virgin, the highest grade. This has to be made by a physical (rather than chemical) process, and meet strict chemical requirements, including levels of oxidation and “free acidity” (a measure of decomposition).

Like any fresh product, olive oil deteriorates over time. “The trouble,” says Ridgeway, “is that it’s quite easy to clean up, say, an oil that doesn’t quite pass the acidity test, and to do it without leaving any chemical markers. It could even taste pretty good, for about three months. Then it will go horribly wrong.”

Michael North, an expert who runs a fresh seasonal olive oil club, says the problem is “huge. The public are just not aware of what’s going on. There’s plenty of oil out there that’s rubbish: last year’s oil or older. Or not even olive oil.”So how can consumers best ensure they’re not being ripped off? Ridgeway recommends paying a sensible price. Unfortunately, a 50cl bottle costing £15 is, on balance, “less likely to have problems” than one costing £2. North urges people never to buy olive oil in a clear bottle (“It oxidises and goes rancid far faster”), and to buy from somewhere you can taste it first.

Both he and Ridegway, though, stress the prime importance of buying young. “Look for a harvest date,” North says. “They’re starting to appear now, albeit on only a few bottles, and they’ll tell you how old the oil is. It’s not an absolute guarantee of quality, but half the battle.”

How to buy olive oil

• Find a seller who stores it in clean, temperature-controlled stainless steel containers topped with an inert gas such as nitrogen to keep oxygen at bay, and bottles it as they sell it. Ask to taste it before buying.

• Favour bottles or containers that protect against light, and buy a quantity that you’ll use up quickly.

• Don’t worry about colour. Good oils come in all shades, from green to gold to pale straw – but avoid flavours such as mouldy, cooked, greasy, meaty, metallic, and cardboard.

• Ensure that your oil is labelled “extra virgin,” since other categories—”pure” or “light” oil, “olive oil” and “olive pomace oil” – have undergone chemical refinement.

• Try to buy oils only from this year’s harvest – look for bottles with a date of harvest. Failing that, look at the “best by” date which should be two years after an oil was bottled.

• Though not always a guarantee of quality, PDO (protected designation of origin) and PGI (protected geographical indication) status should inspire some confidence.

• Some terms commonly used on olive oil labels are anachronistic, such as “first pressed” and “cold pressed”. Since most extra virgin oil nowadays is made with centrifuges, it isn’t “pressed” at all, and true extra virgin oil comes exclusively from the first processing of the olive paste.

For further information, see extravirginity.com. Extracted from Extra Virginity: The Sublime and Scandalous World of Olive Oil by Tom Mueller.

 How to tell if your olive oil is the real thing

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Rapper Heavy D died from pulmonary embolism caused by DVT

December 29, 2011

Dwight Arrington Myers ak 006 Rapper Heavy D died from pulmonary embolism caused by DVT

Deep vein thrombosis is primarily a blood clot in a deep vein…think of a blood clot as a piece of tissue in your vein…it shouldn’t be there …but it is..now if it dislodges from its location, it becomes a piece of scab traveling in your vein and if it travels to the lungs…it becomes known as a pulmonary embolism. In either case, a very serious condition requiring emergency medical care. Certain diseases,life choices, trauma,infection,hospilizations,or pregnancy can increase the risks of deep vein thrombosis(DVT). So ask your family physician if you are at risk!

Pass it on and save a life…

http://www.yepod.com/?p=25541

Dr Anthony

Yepod.com   


poweredbyguardianREV Rapper Heavy D died from pulmonary embolism caused by DVTThis article titled “Rapper Heavy D died from pulmonary embolism caused by DVT” was written by Sean Michaels, for guardian.co.uk on Thursday 29th December 2011 10.57 UTC

The sudden death of Heavy D was down to a pulmonary embolism caused by deep vein thrombosis, coroners have announced. The rapper was killed by a blood clot that probably formed in his leg during a flight from London to Los Angeles, and which made its way fatally to his lung.

Although Heavy D’s autopsy was initially inconclusive, the Los Angeles county department of coroner have now completed their investigation into the 44-year-old’s cause of death. When Heavy D was found outside his home on 8 November, collapsed but conscious, the clot in his lungs was likely restricting blood flow and putting severe pressure on his heart. He died at Cedars-Sinai Medical Centre.

Heavy D’s flight “is the connection”, Craig Harvey, chief coroner investigator, told the New York Daily News. “He had reportedly been in London for about six weeks and had returned to LA within the preceding week or so.” The 344lb (26 stone) rapper was found to have deep leg vein thrombosis, pointing to the formation of a clot during the long flight. Air travel, as well as obesity, are common causes of thrombosis.

A pulmonary embolism occurs when a blood clot formed in another part of the body migrates to the lungs and blocks an artery.

Despite early reports, pneumonia has been ruled out as a cause of death. So have drugs, despite a toxicology report that found medication in Heavy D’s system. “He was treating himself with cough syrup,” Harvey told the LA Times, “but it was not contributory.”

Born Dwight Arrington Myers, Heavy D was one of hip-hop’s leading voices in the late 80s and 90s. As leader of Heavy D & the Boyz, he released five top 40 albums in the US and the international hit single Now That We Found Love in 1991. Before returning to the stage in October 2011, Heavy D had not performed live in 15 years.

 Rapper Heavy D died from pulmonary embolism caused by DVT

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Patients should have online access to medical records, says report

December 23, 2011

Woman filing medical reco 007 Patients should have online access to medical records, says report

Patients having access to their medical sounds like a good idea…as long as they attempt to use it to educate themselves and generate questions to ask their doctors. I support this idea 100 percent and look forward to it’s inception. This could facilitate patients take a more active role in supporting their health decisions.

http://www.yepod.com/?p=24491

Pass it on,

Dr Anthony

http://www.Yepod.com


poweredbyguardian Patients should have online access to medical records, says reportThis article titled “Patients should have online access to medical records, says report” was written by Denis Campbell, health correspondent, for The Guardian on Friday 23rd December 2011 01.27 UTC

NHS patients will be allowed to see and edit their medical records under proposals in a government-commissioned report.

The plan is contained in a report that an expert advisory group, headed by Professor Steve Field, the coalition’s NHS troubleshooter, is finalising before handing it to the Department of Health.

The changes would enable patients to view their whole medical history, study the result of diagnostic tests and see what drugs they have been prescribed before. They would also be able to check on their next appointment and order a repeat prescription.

The NHS Future Forum will outline the significant extension of patients’ rights in a report on how greater availability of information in the health service can improve treatment and make users of NHS services feel more involved and empowered.

The plan will help the health secretary, Andrew Lansley, finally realise his longstanding goal of an “information revolution” intended to help put patients more in control of their own care.

The scheme could be operational in England inside three years, the forum believes.

One forum member said that in an age when citizens could access their bank account details from their home computer, it was “unsustainable” for existing restrictions on patients’ access to their medical records to continue.

Currently, patients’ right to see their records is protected under the NHS Constitution but they have to apply for access and explain why they want to see them.

Although the recommendations are not binding on the government, Lord Howe, the health minister in the House of Lords, has already welcomed that plan. “We fully support patients having online access to their personal GP records. Our vision for a modern NHS is to give patients more information and control over their health,” he told today’s Times.

Patient groups are also likely to back the plan. “Many patients phone our helpline saying that they are having difficulty accessing their medical records from their GP, even though the NHS Constitution states that they have a legal right to do this,” said Katherine Murphy, chief executive of the Patients Association.

But, in a sign that not everyone involved may welcome the change, Murphy added that patient confidentiality was crucial.

“Health records are among the most personal and sensitive information kept about patients and they must be protected. There must be a guarantee that all patient data will be protected and that it will not be possible to trace back information to an individual”, she said.

Family doctors’ attitudes to the plan will be vital. GPs may not back the idea of patients having such access, which could see them allowed to suggest corrections. But the forum’s report will highlight the positive effect on doctor-patient relations of introducing such a scheme..

 Patients should have online access to medical records, says report

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The incredible shrinking laboratory or ‘lab-on-a-chip’

December 2, 2011

Blood samples are picture 007 The incredible shrinking laboratory or lab on a chip

As technology races ever so quickly into the future, it does so by making daily activities in the laboratory much more easier to perform tests. It’s amazing how much information can be retrieved from just one drop of human blood. The benefits of such tests being done more quickly and inexpensive is that we can now do them more frequently. By adopting a more active role in our health and performing frequent blood tests , we can detect an underlaying disease before it progresses too far…and perhaps save our own lives..

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poweredbyguardian The incredible shrinking laboratory or lab on a chipThis article titled “The incredible shrinking laboratory or ‘lab-on-a-chip’” was written by Alok Jha, science correspondent, for guardian.co.uk on Monday 28th November 2011 15.27 UTC

When a doctor wants to carry out a test, she will probably prick you with a needle, fill up several test tubes of your blood, label, package and send them to some centralised hospital laboratory. Technicians will then take the contents, perform the various biochemical analyses needed, write up the results and send back the documentation in a few weeks, perhaps longer if there’s a backlog.

The process is slow and labour-intensive. What if you could reduce the whole business to a few minutes? What if, for the majority of ailments or questions, the doctor only needed a drop of your blood and could test you for viruses or cancers while you wait in her surgery? With a lab-on-a-chip, that is already possible.

Quick tests are not a new idea – pregnancy tests can be done at home and diabetics can quickly and easily measure their blood sugar levels using only a drop of blood – but complex diagnoses still need labs and technicians.

“With a lab-on-a-chip you can do a quick diagnostic test and get information right there, which is very useful when somebody’s got a disease that’s got a very short timeline to be treated,” says Mark Morrison, CEO of the Institute of Nanotechnology in Stirling, UK. “What it effectively does is miniaturises and compacts all the different processes that a researcher or a technician in the diagnostic lab uses.”

The lab-on-a-chip shrinks the pipettes, beakers and test tubes of a modern chemistry lab onto a microchip-sized wafer of glass or plastic. Perhaps you want to know which viruses are in a sample of blood? Or, on the battlefield, which biological warfare agent is present in a soldier’s bloodstream? Put in a drop of blood at one end and the carefully carved channels take its constituent molecules past a circuit of nanometre-sized chemical and physical tests that poke, prod and characterise them to answer your question, however complicated. A chip developed by the University of Alberta, for example, can screen for chromosome mutations that cause a range of cancers.

The platform blurs nanotechnology, biotechnology and micro-electronics. And it is not specific to medicine – it is being developed for environmental monitoring of pollutants and, increasingly, in basic scientific research to speed up the once-tedious aspects of examining genes or testing the properties of new materials.

Prof Tom Duke at the London Centre for Nantechnology has been working on a chip that can detect whether a blood sample contains HIV. Current tests require testing in large laboratories staffed by skilled clinicians, which is a hindrance if you want to test people in resource-poor countries where the disease is rife.

Duke’s chip simplifies that process using a sensor that only requires a drop of blood at one end. The blood is separated into its parts by an array of nanometre-sized silicon pillars in the sensor and the biggest bits – such as blood cells and large proteins – are trapped. Any virus particles pass between the pilars to the other end of the sensor, where they are attracted to a series of tiny cantilevers coated with antibodies. These are, in essence, mini diving boards that bend when something lands on them, and that deflection can be measured by bouncing a laser off them. The more the diving boards are deflected, the more virus is present. “This platform can be used for pretty much any viral or bacterial disease,” says Duke.

There are several advantages to the lab-on-a-chip approach, beyond the convenience of being able to test in the field. The test sample required is much smaller because of the sensitivity of the chip, which is useful if you need to measure trace gases in the atmosphere or the very earliest stages of a disease when the chemical markers in the blood are low in number and would probably be missed by standard tests.

“Potentially you can detect the presence of, for example, cancer or diabetes at a much earlier stage and then treat it more effectively,” says Morrison. “If you treat the disease earlier on, you have a much greater chance of success.”

The Simbas chip, designed by a team of researchers led by Ivan Dimov at the University of California, Berkeley, can detect a biological component in blood at a concentration of around 1 part per 40 billion. “That can be roughly thought of as finding a fine grain of sand in a 1,700-gallon sand pile,” says Dimov. The self-contained chip can get results from a drop of blood in 10 minutes, without the need for any external pumps, tubes or power supply.

Researchers interested in basic physiology are also finding a use for these sophisticated mini laboratories. Scientists at Harvard University have created a lung on a chip that contains several types of tissue and can be used in experiments to understand basic function. They can simulate flowing blood, introduce pollutants and toxins to see how the “lung” reacts and even stretch and contract the cells to simulate breathing.

The technology will no doubt get faster, cheaper and more abundant. But there are some ethical questions coming along the pipeline, along with the technical ones. Most important, while it is still in its infancy and still relatively expensive, who gets access to it? And, since many of the devices will be used to test for an individual’s susceptibility to specific genetic diseases, another question is who should be able to access to that information? “As a scientist I’d say screen everybody for every disease because then you know who is going to get something and you can treat them early on,” says Morrison. “But that’s maybe looking at it from a utopian point of view.”

The dystopian alternative is a precautionary note rather than an inevitability and, in any case, debates around future access to genetic and medical data are already under way, thanks to a rapidly improving arsenal of medical and environmental sensors. Miniature laboratories on silicon and glass chips are another, invaluable tool in that arsenal.

The Guardian is working in association with the European Union’s NanoChannels project to create a portal for information on the technical and ethical challenges associated with nanotechnology

 

 The incredible shrinking laboratory or lab on a chip

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Genital warts vaccination to be offered to schoolgirls

November 25, 2011

Gardasil vaccine 007 Genital warts vaccination to be offered to schoolgirls

Genital vaccination for school girls? That’s right the world continues to change…for the better or worst…it’s all depends on your point of view…can you pass the warts please or not..

Pass it on,

Dr Anthony 


poweredbyguardian Genital warts vaccination to be offered to schoolgirlsThis article titled “Genital warts vaccination to be offered to schoolgirls” was written by Denis Campbell, health correspondent, for The Guardian on Thursday 24th November 2011 20.38 UTC

Schoolgirls across the UK will be offered immunisation against genital warts, one of the most common sexually transmitted infections, in a move welcomed by doctors.

It will expand the existing vaccination against cervical cancer for 12- and 13-year-olds.

The change will take place at the start of the next school year in August and September 2012. All 12- and 13-year-old schoolgirls will be offered a vaccine called Gardasil, which protects against the two strains of the human papilloma virus (HPV) that cause 70% of cervical cancers and also two other strains that produce 90% of genital warts.

It will replace Cervarix, which has been used since immunisation began in 2008 but only offers protection against cervical cancer.

The drive against HPV has been successful. Latest official figures show that 77% of 12- and 13-year-olds, and 84% of 14- and 15-year-olds, have voluntarily received the full course of three HPV jabs, either at school or at their GP’s surgery – the highest uptake in the world.

Ministers have decided to make the switch after advice from their independent advisers, the Joint Committee on Vaccination and Immunisation, and studying evidence collated by the Health Protection Agency.

About 75,000 people a year in England are diagnosed for the first time with genital warts, but the total number of those developing it annually in the UK is around 161,000 people, once those who find that it has recurred despite treatment are included.

Professor David Salisbury, the government’s director of immunisation, said the switch had been made after examining new evidence from Australia where Gardasil had greatly reduced cases of genital warts among both girls and boys while preventing the same number of deaths a year from cervical cancer as Cervarix, estimated at 400.

“We looked at the science and we looked at the price. We have reflected the changes in scientific knowledge that has become available since last time. They are not huge changes – we still prioritise the prevention of cancer – but based on all these things the winner is Gardasil,” said Salisbury.

Dr Peter Greenhouse of the British Association for Sexual Health and HIV said the organisation was delighted by the news. He said that if 70% of girls continued to be immunised against HPV, “we should expect to see genital wart infections start to reduce in teenage girls within five years, and slightly later in boys.

“If we continue to vaccinate just 70% of 12- to-13 year-old girls, we can predict that genital warts should be eradicated in heterosexual women and men within 20 years, through the herd immunity effect,” he added.

Greenhouse said Gardasil should be made available to young gay men on their first visit to a sexual health clinic in order to protect them against anal and oral cancers as well as genital warts.

The Aids charity the Terrence Higgins Trust also welcomed the decision because “it makes sense in terms of improving women’s health and will also save the NHS millions.”

But the charity called on ministers to offer the vaccine to all boys to protect them against some male cancers.

A British Medical Association spokeswomen said: “The latest evidence shows that Gardasil has superior public health benefits and is more cost effective.:

Dr Tony Falconer, the president of the Royal College of Obstetricians and Gynaecologists, said: “The quadrivalent vaccine will also protect against the strains of HPV that cause genital warts, which are unpleasant and the cause of much psychological distress for sufferers.”

The Health Protection Agency said: “Warts are a common sexually transmitted infection in the UK, and as a result of this decision we expect to see a reduction in the number of diagnoses over time.”

“We understand that the choice of the quadrivalent vaccine [Gardasil] in the UK followed a competitive tender. This tender was informed by a detailed scientific study comparing the two available vaccines against a range of criteria, including scientific qualities and cost effectiveness.”

 

 Genital warts vaccination to be offered to schoolgirls

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Why women want to gain weights

November 18, 2011

Evelyn Stevenson powerlif 007 Why women want to gain weights

Weightlifting is an excellent way to maitain a fit and firmer body. I am not surprise that more women are finding that this form of exercise can be of great benefit. I myself workout 3 times a week with dumbbells in my apartment. Remember one rule…start slow and gradually increase the weights. Always consult with a doctor before taking on a new exercise routine.

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poweredbyguardian Why women want to gain weightsThis article titled “Why women want to gain weights” was written by Sarah Ditum, for The Guardian on Thursday 17th November 2011 21.00 UTC

Over the last 100 years or so, the pursuit of female physical perfection has included organ-crushing corsetry, starvation and the surgical insertion of synthetic implants. But finally, it seems, the healthy goal of becoming physically strong is gaining popularity.

You may think this is nothing new. But Evelyn Stevenson, model, personal trainer and British champion powerlifter (last weekend, she won silver at the World Championships), says she has only recently seen a change in her clients’ ambitions. “They used to say: ‘I want to tone up and lose weight.’ But weight isn’t the best indicator [of fitness],” she adds. “Recently, a new client said: ‘I really like the athletic build that Jennifer Aniston has.’”

This growing acceptance that strong physiques are not anti-feminine has been reinforced by the prominence given to female competitors in the run-up to the London Olympics – in mainstream media as well as on the sports pages. When Victoria Pendleton followed up her cycling gold medal in 2008 by turning FHM cover girl, it felt like something new: the world had decided women could be both sporty and sexy.

Nevertheless, Stevenson says she often has to reassure clients that weightlifting is not necessarily a path to a bulging body-builder’s physique. Low testosterone levels mean women are unlikely to bulk up, and a training programme focused on larger weights rather than lengthy sessions will lead to a toned, rather than ripped, appearance.

Perhaps the best thing about pursuing strength over slenderness is that it can transform your relationship with your body from one of criticism (why can’t I fit into those jeans?) to one of pride (look at the size of the weight I’m benchpressing). “Being fit is – I don’t want to say sexy, but empowering,” says Stevenson. “I know I can carry my bags home from Sainsbury’s.”

 

 Why women want to gain weights

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Resveratrol pills may mimic effects of exercise and low-calorie diet

November 4, 2011

grapes 001 Resveratrol pills may mimic effects of exercise and low calorie diet

Resveratol has been known for some time to be of benefits to a healthy life-style. Recent studies have uncovered additional qualities that may encourage more persons to add resveratrol to their diets. Reducing blood sugar is a wonderful metabolic side effect that can benefit the millions of people diagnosed with diabetes. So perhaps resveratrol deserves a closer look at…..

http://www.yepod.com/?p=17431

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Dr Anthony

logo smaller with star Resveratrol pills may mimic effects of exercise and low calorie diet


poweredbyguardian Resveratrol pills may mimic effects of exercise and low calorie dietThis article titled “Resveratrol pills may mimic effects of exercise and low-calorie diet” was written by Nic Fleming, for The Guardian on Tuesday 1st November 2011 16.08 UTC

Taking supplements of a substance found in grape skin can lower sugar and fat levels in the blood and reduce blood pressure, according to a small study.

Scientists who gave tablets containing purified resveratrol to obese men found it had some metabolic effects similar to those from exercise and calorie restriction, including lowering blood pressure and blood sugar levels.

Research in animals over the past decade has suggested the compound can slow the development of age-related diseases and increase lifespan. However, these studies have attracted growing criticism and have yet to be replicated in humans.

“The effects of resveratrol were modest but they consistently point towards beneficial metabolic adaptions,” said Prof Patrick Schrauwen of Maastricht University in the Netherlands, who led the new study. Although the chemical is found naturally in grape skin and red wine, there is no suggestion that it would be possible to ingest enough of it from these sources to gain the beneficial effect.

Prof Schrauwen and colleagues gave 11 obese men either a daily 150mg resveratrol supplement or a placebo for 30 days. Four weeks later, the two groups swapped over so that those who took the supplements first time around were given placebos and vice versa.

Regular measurements showed resveratrol lowered blood sugar levels and improved insulin sensitivity, as well as cutting triglycerides – fats found in the blood that can increase heart disease risk. Resveratrol also reduced both sleeping and resting metabolic rate and cut blood pressure.

Previous research has shown that calorie restriction can extend lifespan in laboratory animals. Some studies suggest it also offers protection from diseases such as cardiovascular disease and type 2 diabetes, though this remains controversial.

Calorie restriction works in a similar way to resveratrol, by triggering the production of a protein called SIRT1 which improves metabolic function and keeps cells healthy in the face of stress.

Muscle biopsies carried out by Prof Schrauwen’s team confirmed that participants taking resveratrol saw increased SIRT1 levels. They also strongly suggested the beneficial effects on metabolism were associated with improved functioning of mitochondria, the energy factories within cells.

“Healthy people are good at switching efficiently from using fat as an energy source to glucose in the blood when it becomes available,” said Prof Schrauwen. “The results of our pilot study tended to suggest that might be part of the link to the beneficial health effects of resveratrol, but that needs further study.”

The results are published in the journal Cell Metabolism.

Prof Schrauwen, acknowledging that his sample size was small, said he was seeking funding for a larger and longer trial. “This is small, proof of principle study, but the results are so promising that I think it is important that we conduct a bigger study,” he said.

 Resveratrol pills may mimic effects of exercise and low calorie diet

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Aspirin cuts cancer risk in people with an inherited susceptibility

October 30, 2011

 aspirin 006 Aspirin cuts cancer risk in people with an inherited susceptibility

Taking aspirin seems to be getting more popular these days…that is good news for the pharmaceutical companies..but can also be good news for the rest of us…perhaps taking aspirin is not only good to take to lower the risk of an heart attack by thinning out the blood, but it may help us lower the risk of developing some types of cancers…only time will tell if this idea has any merit.. consult your physician before taking or adding any medication to your diet.

http://www.yepod.com/?p=16840

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Some people with a family history of cancer could halve their risk of developing the disease by taking daily doses of aspirin, according to the results of a 10-year trial of the treatment.

The study shows that regularly taking the medicine cuts the risk of bowel cancer by more than 60% in those with a particular genetic predisposition to get the disease – as well as reducing the risk of other hereditary cancers.

Scientists who led the study said people with several family members with cancers other than breast, blood and prostate might be advised to start taking aspirin daily from the age of 45.

They said those without a family history of the disease might also consider doing so, but that they should make a personal assessment of the risks and benefits and get medical advice. Anyone thinking of taking the drug regularly should consult their doctor first.

Doctors already prescribe low, daily doses of aspirin to people at increased risk of heart attacks and strokes, and evidence has been growing of anti-cancer properties for 20 years. However, this is the first long-term, randomised controlled trial to show such an effect.

The trial involved people with Lynch syndrome, a genetic abnormality that predisposes carriers to develop bowel cancer and other solid organ cancers including endometrial, ovarian, stomach, kidney, oesophageal, brain and skin tumours.

The condition affects at least one in 1,000 people. Carriers are around 10 times as likely to develop cancer and often do so at a young age.

Professor John Burn of Newcastle University, who led the study, estimated that if all 30,000 or so people with Lynch syndrome in the UK were to start taking two aspirin tablets a day then some 10,000 cancers would be prevented over the next 30 years, saving about a thousand lives. The downside of the treatment is that around an extra thousand people would develop stomach ulcers as a side-effect.

“People with a genetic susceptibility are a model system,” said Burn, whose work is published on Friday in the Lancet online. “They are more sensitive to the environmental triggers to cancer.

“If we can do something to change cancer progression in people at high genetic risk, then that’s telling us what we might all benefit. But we are not making a recommendation for the general population. Everyone can take this evidence and make their own choice.

“In between you have the people who have a family history [of cancer]. Those individuals may well decide to put themselves on aspirin and that would be a reasonable conclusion from the data currently available.”

Between 1999 and 2005, about half of a group of 861 Lynch syndrome carriers were given two aspirins (600mg) a day, while the rest took placebos.

By 2010 those who had taken aspirin for at least two years were 63% less likely to have developed bowel cancer.

Looking at all forms of the disease, almost 30% of those in the placebo group developed a Lynch syndrome-related cancer, compared with 15% for those given aspirin.

The most common side effects associated with taking aspirin are gastrointestinal ulcers and stomach bleeding. There is also an very small increased risk of haemorrhagic stroke, in which a blood vessel in the brain bursts.

There was no difference in the proportions of the study groups suffering such side-effects.

Burn added that he takes low-dose aspirin tablets as a preventative measure. “That was a balanced judgment based on weighing risks and benefits. I know I might get an ulcer or a cerebral bleed but I’d rather not have a heart attack, stroke or cancer. That’s my choice.”

Aspirin is a synthetic version of the active component of willow bark, salicylic acid, which has been used as a medicine for its anti-inflammatory properties for hundreds of years. Salicylates also trigger programmed cell death to help diseased plants contain the spread of infection.

“It’s not a huge stretch to think that if salicylate induces programmed cell death in plants to kill infected cells, maybe it’s doing similar things in the animal kingdom to enhance the death of aberrant cells causing cancer,” said Prof Burn.

“This adds to the growing body of evidence showing the importance of aspirin, and aspirin-like drugs, in the fight against cancer and emphasises how critical it is to carry out long-term international research,” said Prof Chris Paraskeva, a bowel cancer expert at the University of Bristol.

On Friday the researchers will launch a website to recruit 3,000 people with Lynch syndrome worldwide to take part in a five-year trial to determine the best dose of aspirin to take.

 

 Aspirin cuts cancer risk in people with an inherited susceptibility

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Breast screening is no longer a no-brainer

October 27, 2011

Breast cancer screening 007 Breast screening is no longer a no brainer

When we speak about breast cancer our thought wonder to a female member or friend who have lost or won their battle. But it must be made clear that men as well, although rare, can develop breast cancer. One thing is clear is that rountine checks with your family can be life saving. So what are you waiting for? Make your appointment today and win the fight!

http://www.yepod.com/?p=16712

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Dr Anthony    


poweredbyguardian Breast screening is no longer a no brainerThis article titled “Breast screening is no longer a no-brainer” was written by Sarah Boseley, for guardian.co.uk on Wednesday 26th October 2011 15.00 UTC

It may seem like a no-brainer to turn up at the breast-screening clinic when the summons falls through the letterbox. Most of us are scared of cancer. Most of us have heard that if you catch it early, there is more chance of a cure.

But for some years now, there has been a growing volume of dissent to this orthodoxy – and it hasn’t come from anti-medical campaigners, suspicious of toxic drugs. It has come from within the scientific community. Those who are asking the big question – is breast screening always a good thing? – are from a group with one of the best-respected scientific pedigrees. This is the Cochrane Collaboration, set up to weigh the totality of scientific evidence and tell us what really works and what does not.

They have been publishing their findings in top medical journals, such as the Lancet and the British Medical Journal, and news organisations have run stories – but every time we have asked the NHS screening programme for a comment, the Cochrane findings have been summarily dismissed. Most scientists, we have been told, do not agree with the Cochrane researchers. Studies are cited that show screening saves lives.

I have felt for some time that there has been an element in all this of “don’t frighten the horses” and, personally, I think it underestimates – nay, insults – the intelligence of women. Screening is not like vaccination. We are not going to infect anybody else if we don’t go for breast screening. If a cancer is missed, it is an individual who suffers, not the population as a whole. But the information we are given in NHS screening leaflets, echoing the official rebuttal of the Cochrane studies, barely mentions any possible downsides to going along.

And, yes, there are downsides. Nobody disputes now that there is some “over-diagnosis” and “over-treatment”. What the X-rays show is often not much more than a tiny spot on a screen. Once upon a time, cancer doctors believed every one of those would, if left, turn into an aggressive cancer with the potential to kill. A couple of decades ago, the approach to breast cancer treatment was root and branch – a “Halsted” mastectomy, named after the surgeon who excised as much of the chest as he could in the belief that he was saving lives. That doesn’t happen any more – now surgery is conservative and as limited as possible. Doctors try to deliver the smallest, most effective, amount of surgery, drugs and radiotherapy because of the long-term damage they can cause.

But just as surgeons have backtracked on radical mastectomy, so now it may be time to backtrack on radical diagnosis. According to the Nordic Cochrane collaboration, not every spot on the X-ray will turn into aggressive cancer. Their statistical evidence – looking at the numbers of women screened in a big Swedish trial in the 1980s compared with those who were not – is that less cancers were found in those not screened. That is because, they believe, some early-stage cancers regress – they disappear again without causing any harm. Others, we know, grow so slowly that women will die at a ripe old age of something else.

Breast cancer treatment these days is very much better than when screening began. Survival rates are high. Urgent treatment of an invisible clump of mutant cells may not be necessary. Screening will always be important and should be available for those who want it – especially for women whose family history or other factors put them at high risk. But women should be told of the potential harms as well as benefits so they can make an informed choice – and where the X-ray picks something up, perhaps she can sometimes be given a waiting and watching option, as in men’s prostate cancer.

But whatever the outcome of the review announced by the government’s cancer director, Professor Sir Mike Richards, the most important thing is that it will have happened. Serious issues will be seriously discussed and women, many of them for the first time, will know that breast screening is not, in fact, just a no-brainer and that there are choices that can be made. Hopefully that will not be frightening, but empowering. Thank you, Sir Mike, for that.

 

 Breast screening is no longer a no brainer

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Coping with the death of a child

October 15, 2011

Nicola Streeten 007 Coping with the death of a child

Dealing with the death of a loved one can be one of the toughest things in life. Many individuals avoid seeking help from friends,family, or professional counseling. If you are finding it impossible to perform you daily living activities or have fallen into a depression, reach out for help before your condition deteriorates. You can overcome your painful loss.

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Dr Anthony 


poweredbyguardian Coping with the death of a childThis article titled “Coping with the death of a child” was written by Jon Henley, for The Guardian on Friday 14th October 2011 23.05 UTC

Billy Edwin Plowman Streeten died on 19 September 1995, aged two years and two months. That’s where we have to begin. No point trying to fudge things. It is, anyway, the reason this article is being written. Or at least, not Billy’s death itself, but the way people – family, friends, strangers, colleagues, his parents above all – dealt with it.

“It’s OK,” says Nicola Streeten, Billy’s mother. “Honestly, it’s completely fine. It was 16 years ago. We’re all right with it now. We realised then we were going through something huge, something absolutely massive, but we knew that eventually it would transform itself into something else, and it has. It’s OK. Really.”

Part of that monstrous experience has been transformed into a remarkable book, Billy, Me & You, published this month. A graphic novel, or more accurately a graphic memoir, drawn from the diary that Nicola kept, it is searchingly honest, and desperately sad at times. At others, it is genuinely very funny. Quite a feat.

“My motivation,” Nicola says, “was to tell a story people couldn’t put down. Not just about me, but questioning people’s responses, society’s response, to trauma and grief. I wanted the laughing and the crying. Not a misery memoir, a book for people who’ve had shit thrown at them. It may be cathartic for some, but for me it was a work of art. Not therapy.”

It would have been different if she’d done it at the time. We’re at her friend and editor’s house next to the British Museum in London. Nicola, 48 now, talks fast and laughs often. The day we meet is, by coincidence, the anniversary of Billy’s death; she and his father, her husband John, 58, have come to London from their Lincolnshire home and had their annual commemorative lunch together. (By the same token, they place a small notice in the Guardian every 19 September: “Our equivalent of putting flowers on his grave.”)

“We’re not at all religious,” Nicola says. “We couldn’t do God. So we kind of invented our own superstitious belief system. And part of that is, every year, we come to London for lunch on the day he died, and John puts the in memoriam in the paper.” But 16 years ago today, they were walking out of the Royal Brompton hospital, clutching their dead son’s possessions.

Billy was born when Nicola was 30. The couple were living in Crouch End, London; she teaching English as a foreign language, he an established artist. “It’s the greatest thing that can happen, when your baby’s born,” she says. “We just wanted to enjoy having a child. We shared the childcare from the start. Thank God – that meant we’d both had a fair innings.”

All Billy’s early tests had been fine; he was a normal baby. “Always on the bottom line of the graphs,” Nicola says, “but he never dropped off. We thought the doctors were being fussy. You never really know, though, do you, when it’s your first? You’re never really sure.”

When he was one, Billy got pneumonia and had to go to hospital for intravenous antibiotics. He recovered, but a shadow on his lung didn’t clear. “Over the next year, they ran every test,” says Nicola. “Cystic fibrosis, cancer, heart, the lot. And he was running around, fine. You could never have told.”

Eventually, a consultant at the Whittington hospital concluded it was asthma. That winter, Billy got ill a lot; coughs, colds, trips to the hospital, lots of medicine. In the summer, just after his second birthday in early July, the family booked a holiday cottage in Orkney. There Billy got really ill. “The doctor told us he needed an air ambulance, to Aberdeen,” Nicola says. “Billy couldn’t believe his luck: a helicopter!”

Back in London, his case was transferred to the Royal Brompton. There, suddenly, the experts announced: this isn’t asthma, this is heart-related. Three congenital deformities; Billy was suffering from pulmonary hypertension.

By early September, Nicola says: “They gave us our options. They could operate, in which case there was a 30% chance of success. They could try for a heart and lung transplant; not recommended. Or they could do nothing, in which case Billy would eventually die, slowly and painfully, because he would end up not being able to breathe.”

The options weren’t really options. “In any case, we’d latched on to the word ‘success’,” says Nicola. “Crazy, because you’d never get in a plane that had a 30% chance of landing safely. We all moved into the hospital, 10 days before. It was going to be a 15-hour op. In the evening, we went to the cinema. There were no mobile phones, of course, so I borrowed my sister’s pager. I was looking at it all through the film.”

Back at the hospital, Nicola and John were told the operation had been a success. Billy was in intensive care. “We were to go and get a good night’s sleep and have a leisurely breakfast,” Nicola says. “Then the next morning, when we got out of the lift, there were nurses running in the corridor. They put us in a waiting room. They said: ‘We’re so sorry.’ And we – extraordinary, isn’t it? – we said: ‘Thank you.’”

The scene after that moment, Nicola and John leaving the hospital, forms the opening page of Billy, Me & You. The book offers acutely observed snapshots of the couple through the decade and a half that follows: their savage grief, deep despair, dreams of suicide; the wildly differing reactions of those around them; Billy’s funeral; their return to work and, gradually, something resembling normality; group and individual therapy; the birth of their daughter Sally; the move to Lincolnshire; Nicola’s new career as an illustrator. It ends with a publisher taking a serious interest in Billy’s story.

The sum is probably more revealing – and certainly more affecting – about the experience of loss and grief than most self-help books. There are instants of crushing realisation (“Shall we go for dinner?” “A bit short notice for a babysitter … Oh yes!”) and of crucifying guilt (“Is it because I walked under ladders on purpose? Had an abortion when I was younger? Punishment from a God I don’t believe in?”).

Moments of dreadful self-doubt, too (“I’m not a mother … But I’m not not a mother … What am I?”); hopeless self-pity (“Nobody said anything to me about Billy … all day long”) and rage (“You want to put a bench in the park in Billy’s name? So I can sit there and watch everyone else’s alive children? Are you completely insensitive – or just an idiot?”) And moments of absurdity (Billy will be going to the crematorium, the funeral director tells them in hushed and Victorian tones, on the front seat of what we call “a hearsette”).

Nobody really tells you, says Nicola, about “the awful arrogance of grief. My capacity for intolerance, that was an eye-opener. I think you just felt like you have a … a licence to be foul to people. There we were, in the middle of this lovely north London suburban life, all parks and mortgages and good schools and organic food and pensions, and I just got so angry with everyone’s obsession with all this bourgeois, crappy stuff. Didn’t they realise how unimportant it all was, compared with what we’d been through?”

The couple spent a year, Nicola says, “very consciously working on it. Just hanging on … Grief and death affect everyone differently, of course. I was seriously worried that John might kill himself, really. We started therapy. I think we both knew very soon that our whole outlook on the world had changed. And then two years later, in 1997, Sally came along. There was life, after this. And things started to pick up.”

But there’s no limit to the extent of human awkwardness around death. Especially the death of a child. “My own pet hate,” says Nicola, “is when people say, ‘Oh yeah, John and Nicola – their baby died.’ Because Billy was a four-year block of my life: the thinking about him, the pregnancy, the two years he was alive, the solid year or more of grieving … That doesn’t feel like a baby, it really doesn’t.”

Struck by the different ways people reacted to her news, she started judging their responses, sometimes silently awarding marks out of 10. The worst, she says, were those who refused, for whatever reason, to acknowledge what had happened. “It could have been worse,” was bad; “Oh, really? My friend’s baby died too,” and “I can just imagine what you’re going through,” were pretty much the pits. Marginally better was “Would you like to come to dinner?” and “You must have another baby.” Best of all was: “I’m so sorry.”

An avid diary-keeper as a teenager, Nicola began writing one again soon after Billy died. She’s glad she did, if only because returning to those journals 13 years later, when she began working with her teenage daughter Sally on the magazine stories that would eventually become Billy, Me & You, she realised the tricks that memory plays.

“I cried every day, for a year,” she says. “In my memory, I only cried once. But it’s in my diaries, written down. Every day. I cried every single day, for a year. Looking back now, it’s clear we were pretty much mental for about five years.” (She didn’t cry once while she was working on this book, though: “It’s the most pleasurable thing I’ve done, about the worst thing that’s ever happened to me.”)

So what is Billy for her, today? There is a fair chance, had he lived, that he’d be starting his first term at university. “He’s there,” she says, “if he comes up. It’s no longer upsetting to talk about him. But he is locked in that moment, locked with us in that time. I can’t really project him into the future like that.”

John and Nicola have a cabinet of “old stuff” at home; a kind of informal archive. There’s a favourite bib of Billy’s; Nicola’s diaries; a milk bottle melted in some long-forgotten sterilisation process; Billy’s death certificate; Nicola’s successful pregnancy test; a letter published, two days after Billy died, in the Guardian’s Private Lives section, from a woman who had lost her baby daughter at three days. The reply that Nicola wrote, concluded: “There is nothing to say for the emptiness inside you, except that time will make the pain less acute.”

In any case, says Nicola, Sally is their focus now: “We wouldn’t want her to be overshadowed by a dead brother, whom she never met. Billy is a memory. But having this book, now, as a product of all that we went through … That’s nice.”

Billy, Me & You by Nicola Streeten is published by Turnaround, £11.99. To order a copy for £9.59 with free UK p&p, go to guardian.co.uk/bookshop or call 0330 333 6846

 

 Coping with the death of a child

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Mapping the body: the sigmoid colon

October 13, 2011

The large Intestine 007 Mapping the body: the sigmoid colon

 Many diseases and conditions can affect the bowels. Constipation is a serious condition commonly seen in adults over the age of 50. Usually a change in diet to include more fiber and water will resolve this problem. Oh my colon!

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Dr Anthony  


poweredbyguardian Mapping the body: the sigmoid colonThis article titled “Mapping the body: the sigmoid colon” was written by Gabriel Weston, for The Guardian on Monday 3rd October 2011 20.00 UTC

It is usually patients not doctors who balk at the sight of a medical instrument being unwrapped. But the flatus tube, used to treat a condition of the sigmoid colon, is one no surgeon relishes.

The sigmoid is an S-shaped stretch of large bowel, about 40cm long, which leads up to the rectum. Its main function is to store faeces until it is ready to enter the rectum and be expelled through the anus, and it is the site of a variety of problems.

Inflammatory bowel disease such as ulcerative colitis and Crohn’s disease may occur here. Diverticulitis, in which little outpouchings of bowel form and become inflamed, is more common in the sigmoid than any other part of the bowel. Small growths called polyps, as well as cancers, also favour this site.

The good thing about investigating sigmoid disease is that this part of the colon isn’t far from the outside world. It is easy to pass a rigid sigmoidoscope into the anus and get a decent view. For a more detailed look patients are sedated so that a flexible sigmoidoscope can be introduced, and biopsies can be taken through this. If necessary, it is possible to remove the entire part of the colon in a sigmoidectomy. Usually, the remaining colon can then be joined to the rectum.

But it is another condition that makes junior doctors quake in their surgical boots. Volvulus is when a part of the bowel twists on the tissue which attaches it to the abdominal wall, forming an obstruction and it is commoner here. Patients are usually over 50 and chronically constipated. In A&E, they describe abdominal pain and not having passed faeces or wind for days. Simple x-rays may show a sigmoid colon so distended that it extends all the way up to the chest-bone.

Although definitive treatment often involves surgery, it is the junior doctor’s job to deal with the acute situation with the help of the dreaded flatus tube. The patient lies on their side and a sigmoidoscope is inserted gently into the back passage. The junior then has to slowly manoeuvre the hollow flatus tube through the sigmoidoscope and into the obstructed loop. The key is to make sure the other end is directed over a bucket and not one’s shoes. The patient’s sense of enormous relief when fluid, flatus and faeces are expelled into the bucket is in inverse proportion to the doctor’s discomfort.

• Gabriel Weston is a surgeon and author of Direct Red: A Surgeon’s Story

 

 Mapping the body: the sigmoid colon

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Mapping the body: gastric pits

September 22, 2011

A close up of a gastric p 007 Mapping the body: gastric pits

The human stomach is a facinating organ responsible for the breakdown of food that will be absorbed into the body. Problems with the stomach is a source of hugh profits for the pharmaceutical companies. Individuals sometimes become dependent on laxatives,acid,or stomachache medications to relieve symptoms. If stomach symptoms do not subside within a week from onset, seek medical attention and allow a doctor to do a complete workup to determine the cause of your problems in your gastic pits .

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poweredbyguardian Mapping the body: gastric pitsThis article titled “Mapping the body: gastric pits” was written by Gabriel Weston, for The Guardian on Monday 19th September 2011 20.30 UTC

There’s a funny kind of hierarchy that exists among the organs. You simply don’t hear bladder surgeons boasting about their art in quite the same way that heart and brain surgeons do. And yet, even the most humble body part has its own complex and fascinating physiology.

I realised this when learning about the structure and function of the stomach. Previously, I had thought of the tummy as a lowly place, a mere dumping ground for anything we might choose to stuff in our mouths. I couldn’t have been more mistaken, and my new-found respect for the stomach gained focus when I read about the gastric pit.

If you look inside a stomach when dissecting a cadaver, or during an operation, it appears like a bag whose surface is thrown into a series of visible folds. These are called rugae, and enable the stomach to increase dramatically in size when it fills with food. What you can’t see with the naked eye is that the lining of the stomach (the mucosa) is interrupted by multiple tiny openings, each of which leads to a tiny hormone-producing tunnel. These are the gastric pits and each one is lined with a number of different types of cell, producing a separate, important gastric secretion.

The cells at the top of the pits produce mucus, which protects the stomach lining against gastric acid. Deeper down are two other cell types. Parietal cells generate stomach acid as well as a substance called intrinsic factor, which enables a vitamin called B12 to be absorbed further along in the gut. The impressively named chief cells secrete pepsinogen which, when it mixes with stomach acid, becomes an enzyme called pepsin. This helps to break down the protein we eat into smaller units that can be absorbed.

The heart may be in charge of pumping blood around the whole body. The brain may be master of all we do. But, at the tissue level, wonders are also to be found in those organs that we may think of as being more ordinary.

Gabriel Weston is a surgeon and author of Direct Red: A Surgeon’s Story

 

 Mapping the body: gastric pits

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Testosterone drops when men become fathers

September 17, 2011

Gymnast on the rings 007 Testosterone drops when men become fathers

More attention should be given to testosterone levels of men throughout their lives. There are many symptoms associated with decreased testosterone levels …one example is depression…many men diagnosed with clinical depression were found to have low levels of this hormone..but once testosterone injestions were administered by qualified physcians…symptoms of depression resolved..so get your testosterone checked out…

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Dr Anthony

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poweredbyguardian Testosterone drops when men become fathersThis article titled “Testosterone drops when men become fathers” was written by Ian Sample, science correspondent, for The Guardian on Monday 12th September 2011 19.00 UTC

The hormone that defines the male of the species slumps dramatically when men become fathers, researchers have found.

Blood tests on 624 men in the Philippines revealed that levels of testosterone dropped substantially over a five year period in those who had children.

Men who devoted at least three hours a day to child care had even less testosterone, suggesting that looking after dependent children helped suppress the hormone. Testosterone is responsible for the male body shape, the distribution (and loss) of hair and a man’s sex drive.

Previous studies have shown that fathers tend to have lower testosterone, but it was unclear whether men with reduced levels were more likely to have children, or whether parenthood pushed testosterone down.

“It’s not the case that men with lower testosterone are simply more likely to become fathers,” said Lee Gettler, an anthropologist at Northwestern University in Illinois. “The men who started with high testosterone were more likely to become fathers, but once they did, their testosterone went down substantially.”

Christopher W. Kuzawa, a co-author on the study in Proceedings of the National Academy of Sciences, said fathers seemed “biologically wired” to help raise children.

“To see dramatic changes in response to family life is intriguing,” said Allan Pacey, an andrologist at Sheffield University. “The observations could make some evolutionary sense if we accept the idea that men with lower testosterone levels are more likely to be monogamous with their partner and care for children. However, it would be important to check that link between testosterone levels and behaviour before we could be certain.”

 

 Testosterone drops when men become fathers

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Mapping the body: achilles tendon

September 14, 2011

Heel 007 Mapping the body: achilles tendon

I have seen many injuries to the achilles tendon while treating patients over the years…most of them were strain/sprain injuries to the tendon or muscle. You must approach sport activity carefully, especially if you are now not as active ….due to family or occupation responsibilities keeping you from daily participation. Warming up and stretching muscles prior to physical activity will reduce your risk to injury.

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Dr Anthony

logo smaller with star Mapping the body: achilles tendon


poweredbyguardian Mapping the body: achilles tendonThis article titled “Mapping the body: achilles tendon” was written by Gabriel Weston, for The Guardian on Monday 12th September 2011 20.30 UTC

There is truth in the view that doctors make the worst patients. I have never seen a person obstruct their own recovery more than a surgical consultant who snapped his achilles tendon while playing tennis.

The achilles is a ropelike band of tissue, which connects the calf muscle to the heel on each side, and is crucial for walking, running and jumping. With time and disuse, the tendon can become weak and prone to rupture. So it’s no surprise that injuries to this part of the body tend to occur in middle-aged men enjoying a spurt of uncharacteristic activity, especially where leaping and pivoting are involved. Tripping or falling from a height are also mechanisms of injury.

When it ruptures, sufferers feel sudden severe pain in the ankle or calf, and may hear an audible “pop”. Diagnosis in an emergency department is usually made by a doctor asking their patient to lie prone, feet dangling off the end of the examining table. On squeezing the calf muscle, an intact achilles will cause the foot to point – the absence of this reaction suggests a rupture. Although competitive athletes may be put forward for surgical repair of their tendons, most patients have their leg immobilised in a cast for at least six weeks.

Far worse than this, though, are fractures to the heel bone (or calcaneum). Such injuries tend to occur after a fall from a height or from severe twisting of the foot, and are known to be so painful that patients may be distracted from other injuries such as spinal or leg fractures, which often occur at the same time. Whether patients have surgery or not, it is usually not possible to start walking for at least three months after breaking your heel, and the incidence of lifelong disablility from chronic heel pain is high.

But after five weeks in a cast for his achilles tendon rupture, my boss decided he simply couldn’t bear to be hampered a day longer. He pulled off his own cast, and sprung out of the door, ready for another day at the hospital. He didn’t get as far as his car before he had ruptured his tendon all over again. Proving impatience is the surgeon’s true achilles heel.

Gabriel Weston is a surgeon and author of Direct Red: A Surgeon’s Story.

 

 Mapping the body: achilles tendon

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Chemotherapy breakthrough could could dramatically reduce side-effects

September 13, 2011

Kim Cattrall has chemothe 007 Chemotherapy breakthrough could could dramatically reduce side effects

Progress is being made in cancer research…side effects experienced by patients during chemotherapy can be reduced or even eliminated in the near future…a better delivery system of introducing anti-cancer therapy can also leave healthy cells intact…the “smart bomb” is here…

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Dr Anthony

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poweredbyguardian Chemotherapy breakthrough could could dramatically reduce side effectsThis article titled “Chemotherapy breakthrough could could dramatically reduce side-effects” was written by Alok Jha, science correspondent, for The Guardian on Sunday 11th September 2011 23.01 UTC

Cancer researchers have developed a “smart bomb” treatment that can target tumours with drugs while leaving healthy body cells intact. The technique means that patients will suffer fewer side-effects from the toxic drugs used in chemotherapy.

The side-effects of cancer therapy – including hair loss, nausea and suppression of the immune system – can be debilitating. In many cases, the effects of the drugs can contribute to the ultimate cause of death.

In experiments on mice, Laurence Patterson of the University of Bradford found that he could localise a cancer drug to the site of tumours and thereby limit its toxic impact in the body. All the animals, which had been implanted with human cancer cells responded to the targeted treatment and saw their tumours shrink. In half the animals, the tumours disappeared altogether. Professor Patterson will present his work at the British Science Festival in Bradford on Monday.

“We’ve got a sort of smart bomb that will only be active in the tumour and will not cause damage to normal tissue,” he said. “It’s a new cancer treatment that could be effective against pretty much all types of tumour – we’ve looked at colon, prostate, breast, lung and sarcoma so far, and all have responded very well to this treatment.”

The drug is based on a modified version of an existing cancer drug called coltrazine. In normal situations, this drug is delivered as part of a patient’s chemotherapy regime and, in addition to attacking cancer cells, it can kill healthy cells, too. “There are many agents currently used in the clinic for the treatment of cancer that are essentially poisons,” said Patterson.

“Normal chemotherapy can often be the cause of death of the patient as opposed to dying from the tumour growth itself. Any treatment that is a poison that can be retained and is only active in the tumour is clearly very attractive.” Patterson’s team has designed a way to make the coltrazine active only when it comes into contact with a tumour. They did this by attaching a string of specific amino acids to the coltrazine, which made the drug inert. In this state, it can wander through the body freely and will not kill any cells it comes into contact with. But when the drug reaches the site of a solid tumour, the chain of amino acids is removed by an enzyme present on the surface of the cancer, called MMP-1. At this point, the coltrazine becomes active and can do its work in killing nearby cells.

MMP1 is used by tumours to break down the cellular environment around itself and to enable the tumour to dig a path through normal tissue. It also gives the tumour access to nutrients and oxygen by encouraging the normal blood supply of a person to grow towards it. “If you can starve that tumour of that blood supply, then you shut off its ability to grow and move around the body,” said Patterson.

In the experiments, he said, all the mice responded to the treatment. “Sometimes, the treatment is so effective, you remove the ability of that tumour to grow – you appear to cure the mouse. In some studies, we were able to cure half the mice: these animals no longer had any tumour growing in them and they appeared healthy for the 60 or so days of the trial.”

An important use of the technique is that it can reach tumours that have spread throughout the body.

Paul Workman, head of cancer therapeutics at the Institute of Cancer Research, said: “This is an interesting new approach to targeting tumour blood vessels that solid cancers need for their growth. The project is still at quite an early stage, but the results so far look promising in the laboratory models that have been studied. If confirmed in more extensive laboratory studies, drugs based on this approach could be very useful as part of combination treatments for various cancers.”

The Bradford scientists hope that, with adequate funding, their drug delivery system could enter phase 1 clinical trials on people within 18 months.

 

 Chemotherapy breakthrough could could dramatically reduce side effects Chemotherapy breakthrough could could dramatically reduce side effects

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Annoying? Yoga? Surely not

September 7, 2011

Yoga 007 Annoying? Yoga? Surely not

I must agree…that yoga is not my first choice when it comes to maintaining a healthy life-style…yes some of the positions you find yourself in are quite silly…but most of my friends seem to benefit from yoga. They seem very focused,organized, and calm in their jobs and social gatherings. Perhaps yoga could be of some good…at least I can work on touching my toes…

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Dr Anthony 


poweredbyguardian Annoying? Yoga? Surely notThis article titled “Annoying? Yoga? Surely not” was written by Sarah Miller, for The Guardian on Tuesday 6th September 2011 20.00 UTC

In addition to being somewhat crazy – a shrink once diagnosed me with borderline personality disorder, which I thought was a bit of a stretch until I realised that, like everyone else, he just wanted to have sex with me – I am a yoga teacher. Should you, recoiling in horror as you read this, find yourself asking, “But how does someone like this become a yoga teacher?”, the short answer is that I gave a man with a beard and his hot wife $3,200. The long answer is … well, I’d like to say that it’s because if I hadn’t become obsessed with yoga I’d probably be dead, because that’s what people always say about things like this. But that would be, frankly, a little overdramatic. Let’s just say that if I didn’t do yoga everything bad about me would just be worse, and what is bad is already bad enough.

Now, because you can’t get something for nothing, there’s a problem: yoga can be extremely annoying. There’s no getting around it. Yoga has moments of such profound annoyingness that after I finished Eat, Pray, Love (I read the ashram section 100 times) all I could think was: “You wrote an entire book about yoga and meditation and you never mentioned, ‘Oh, by the way, sometimes you will want to punch these people in the face’.”

And this is where I perform my public service; in yoga we call that a seva (how annoying is that?). All the stuff Elizabeth Gilbert was too high on homemade pizza and Javier Bardem penis to mention, you need to know. Everyone’s always telling you how great yoga is, and that’s true, but then you go and maybe the studio smells like onions steamed in cat pee, and it might have been helpful to know about that beforehand.

You need to know exactly what will disturb you before you get there, so you can prepare; and you should also know that, even though everyone around you will seem perfectly unperturbed, someone feels your pain. Oh, and by the way, I want to underscore that what follows below is what bugs me about yoga; everything else is a glittering gift from Lord Shiva. Namaste!

People who just saw each other yesterday will hug like one of them was just rescued from a burning plane. I’ve always thought of a hug as a slightly protracted, lightly physical way of saying hello to people I know fairly well.

But regular practitioners of yoga see hugs as a great way to spend an afternoon. You will want to stare at them and wonder, “Are they really pressing their whole bodies together?” (yes); “are their eyes closed?” (they are); “do they really have dreamy looks on their faces?” (yes, yes, yes). But remember, while you’re staring you’re wasting valuable time in which you could be cultivating your “I am not the sort of person who likes to be hugged for long periods of time” vibe. This is easier said than done because you will sometimes see people at yoga – people you actually know – with whom you may wish to make brief, friendly physical contact. Engage in such exchanges as you wish, but realise that you are setting yourself up as a person who willingly receives hugs, and these people will not take the extra mental step to say, “Oh, but above-the-waist hugs”, or “Hugs that only last a second”.

Make no mistake: these people are looking to soul-blend. To avoid, arrive early. Lie down with closed eyes. Bring flip-flops – essential for a hasty exit.

During hard poses, women and gay men will remain silent and straight men will laugh self-deprecatingly. Imagine being at a gym. Men are lifting heavy weights. They strain, grit their teeth, sweat. But they don’t laugh. So why, here, as they sink into their thighs in Warrior Two or lift their chest skyward during Upward Facing Bow, do they feel the need to let out a little chuckle? You are witnessing an unconscious assertion of masculinity. That little laugh is their way of letting you know that hey, they’re not really embarrassed about being so bad at this, because they’re not even supposed to be here, they’re good at other things, like, for example, sitting in an airport bar working their way through a double scotch, a bowl of nuts and a Two and A Half Men re-run on the corner TV.

Of course, there is also the other type of straight guy in yoga, the guy who can wrap his arms around his ankles and turn himself into a perfect circle. Why, you ask, does this man wear his hair in a bun, on top of his head? There are some secrets that no amount of enlightenment will reveal. I will tell you this: these guys tend to get a lot of ass, so laugh as you will, but know that they’re getting the last one – upside-down.

There will be yoga overachievers. You will be doing Cat-Cow at a normal pace, and they will be bucking and heaving like mechanical bulls. You will be expending an amount of effort somewhere between “challenging yourself” and “able to retain sufficient muscle strength to remove shampoo bottle from shower caddy”. They will be straining, grunting, grimacing. Then, when class is over, and everyone does that weird little bow, the yoga overachiever will bow down for, roughly, an hour. Seriously. You will have put on your flip-flops (good job!), hightailed it away from the would-be hugger/soul-blenders, made and consumed a meal, masturbated to some violent pornography and be just about to crawl into bed, and they remain on the floor in the yoga studio, thanking God for making them, well, them.

There are teachers and students who think flexibility is some kind of indication of how good a person you are. While we certainly hold tension, trauma and rigidity in our limbs and joints and muscles, there is no reason to imagine there’s some absolutely direct correlation between how well we can move and how functional or healthy our mind is. I seriously doubt that Albert Einstein or Susan Sontag had less flexible minds than, I don’t know, Rodney Yee. My point is, some physical limitations can be aided through the practice of yoga and some can’t and no one needs the increased pressure of someone telling them, every time they strain to get their heels on the floor in Downward Facing Dog, that this is because their mind is all screwed up.

So if your teacher tells you that we hold a lot of stuff in our hips and hamstrings and as we begin to let this stuff go and become our authentic selves we will be able to wrap our arms around ourselves eight times, look around the room. You will probably see a guy who can do that, while smiling, and I’ll bet that you will eventually hear from someone in the class about the time he flew into a rage and broke a car window.

Teachers talk like Yoda’s mum. If you were to ask your yoga teacher, “Can my newly authentic hamstrings help the angry guy?” she might say something like, “That depends on whether they were coming from a space of pure intention.” The word “honour” is used a lot, as in “honouring yourself” or “honouring your practice”. Other popular words include “joy”, “integrity”, “space” (not as in outer space, as in “Go into a space of …”) and “place” (not as in “that place next to Shoe Pavilion”, as in “Let yourself come into a place of …”). When class is over, the teacher will say something like, “Bow to your inner wisdom”, or “Take a moment to thank yourself for committing to your practice”, which always makes me intone the prayer: “Please, God, make me less fat than I was an hour and a half ago.”

The worst part about yoga world vocabulary, of course, is how quickly you find yourself learning and using it. The hope is that because yoga has made you – I’m sorry, I mean, allowed you to open up a space to become – so much more self-aware and less narcissistic, you will only talk this way in front of other people who talk like that too. And now that you are friends with so many of them, because you have, after so thoroughly mocking this world basically joined it, that means practically everyone you speak to.

“How are you?” is not a simple question at yoga. No one at yoga is ever just fine. They’re “working through a lot of heavy stuff”, or “dealing with a lot of craziness”. That said, when people ask you how you are, don’t say anything bad. If you are broke, the universe is just trying to teach you a lesson about how much you already have. If someone dumped you, the universe removed that person from your life for a reason.The universe is very busy in the yoga world.

So yes, in the beginning it’s all about slipping the car keys inside the flip-flops so that all the tools of your escape are in a neat little package. But just keep showing up. In no time you will become sufficiently like all these people that they won’t bother you at all. And then some crazy asshole will make fun of you. Is the circle of eternity beautiful or what?

 

 Annoying? Yoga? Surely not Annoying? Yoga? Surely not

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Get Ripped Abdominals

September 2, 2011

There are a lot of fitness gurus out there ….but Mike Chang teaches you the common sense of getting fit. ..abdominals fitness…no secrets..he tells you how it is….he does an excellent job of explaining what needs to be done to get maximum results in shaping your body…I give this guy a thumbs up…

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Ebola: the solution may be in sight

August 28, 2011

Colorized transmission el 007 Ebola: the solution may be in sight

Research advancements into the understanding of the Ebola virus and eventually a cure will no doubt lead way to other many discoveries. Science is at the verge of a flood of discoveries that will change the destiny of medicine forever.


poweredbyguardian Ebola: the solution may be in sightThis article titled “Ebola: the solution may be in sight” was written by Robin McKie, for The Observer on Saturday 27th August 2011 23.06 UTC

One of the world’s most feared pathogens, the Ebola virus, has a key structural weakness that could be vital in developing drugs to treat the fevers it triggers, US researchers announced in Nature last week. The group say they have bred mice that produce low levels of a protein known as Niemann-Pick C1 which transports cholesterol inside cells. The mice then survived exposure to Ebola, which causes a haemorrhagic fever, and to a cousin pathogen, the Marburg virus.

“This research identifies a critical cellular protein that the Ebola virus needs to cause infection and disease,” said one of the lead scientists in the project, Sean Whelan of Harvard Medical School. “It also improves chances that drugs can be developed that directly combat Ebola infections,” he said.

Ebola fever was first detected by doctors in the 1970s in villages along the Ebola river in the Democratic Republic of Congo and is usually fatal in humans. There have been at least two dozen Ebola outbreaks in Africa though doctors still do not know exactly how the virus is spread. There are no vaccines or drugs to fight it.

The virus is known to interfere with the cells that line the interior surfaces of blood vessels and with the process of blood coagulation. As a result, it causes blood vessel walls to become damaged and to rupture.

The new research announced at Harvard is therefore extremely important. It indicates that the protein Niemann-Pick is used by the Ebola virus to get deep inside cells. “This virus needs this protein,” said Kartik Chandran, of Albert Einstein College of Medicine in New York. “Mice that have less of this protein are very resistant to being killed by Ebola and the Marburg virus.”

Crucially, Chandran has also been involved in work that led to the discovery, in 2005, of a compound that has demonstrated considerable promise in being able to block the Niemann-Pick protein in human cells, according to a separate paper that was published in Nature last week. “Essentially, this compound can block infection by the virus,” said Chandran.

The compound has not yet been tested in mice, and would still need to show it is effective in non-human primates. Chandran said blocking Niemann-Pick in the long term would probably cause illness.

The researchers involved in the studies say they are very optimistic that the new understanding they have built up about the behaviour of the Ebola virus and the means by which it gets into cells may eventually lead to treatments. However, they acknowledge it will take many years, and possibly even a decade of further research and studies, before treatments would be available for human use.

 

 Ebola: the solution may be in sight Ebola: the solution may be in sight

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Dr Dillner’s health dilemmas: should I give up fizzy drinks?

August 27, 2011

A glass of cola 007 Dr Dillners health dilemmas: should I give up fizzy drinks?

It is a challenge for newly diagnosed diabetics to make the necessary changes in their diets to manage their health. No one likes to be told what they should or shouldn’t eat, especially after years of indulging the finer foods of life. If you are beginning to limit colories in the hope of controlling your sugar levels, a good place to start is eliminating all pop drinks (I won’t mention the brand names here…)…drink water,milk,green tea ,etc . The battle on diabetes is won by making small adjustments and avoiding those foods with a high glucose index…live longer…live happier..health matters..

Pass it on,

Dr Anthony

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poweredbyguardian Dr Dillners health dilemmas: should I give up fizzy drinks?This article titled “Dr Dillner’s health dilemmas: should I give up fizzy drinks?” was written by Luisa Dillner, for The Guardian on Monday 22nd August 2011 20.00 UTC

The problem

On a hot day do you reach for a cool can of Coke or a glass of water, and does it matter? Obesity (the body doesn’t seem to regulate its appetite in response to calories in drinks so the sugary drinks are extra calories), dental caries and an increase in diabetes are uncontested risks of drinking sugary fizzy drinks. Fatty livers and pancreatic cancer have also more recently been linked to a hefty intake of sugary, fizzy drinks (up to four cans a day) by researchers, but the studies are not conclusive.

Those of us watching our weight, meanwhile, may have switched to diet drinks, which contain artificial sweeteners, some many hundreds of times sweeter than natural sugars, but without the calories. Coca-Cola’s website says Diet Coke, Coke Zero and Lilt Zero contain aspartame and acesulfame-K. Slimline drinks such as Schweppes slimline Canada Dry ginger ale contain a blend of aspartame and saccharin.

The dilemma

Aspartame has been dogged by controversy ever since it was approved as a food additive over 35 years ago. A report in the Daily Mail last week said that the European Food Safety Authority (EFSA) is being asked to bring forward a safety review of it by members of the European parliament following a Danish study showing an increase in premature births in mothers drinking diet drinks and research showing cancer growth in mice who were fed aspartame.

The EFSA will report in 2012 instead of 2020 but has already said these recent studies have not made them change their opinion on aspartame’s safety. Yet anti-aspartame activists have long claimed it causes brain tumours, multiple sclerosis, blindness, headaches, depression and birth defects. The cause, they say, may be that the body metabolises aspartame by breaking it down to toxic substances, namely methanol and then formaldehyde (which bodies are pickled in at medical school for dissection purposes) and formic acid. But the amounts of these metabolites are small. The US Food and Drug Administration (FDA) says you would need to drink 21 cans of diet sodas a day to approach the recommended safe limit for aspartame and its metabolites.

Aspartame has been cleared as safe in the US and Europe, but you may think there’s no smoke without fire. Some supermarkets stopped using aspartame in their own branded diet products a decade ago. If there is even a whisper of a health scare about a drink you don’t need shouldn’t you opt for a healthier, cheaper alternative such as tap water?

The solution

Don’t be scared by health scares, some of which are urban myths. We don’t absorb aspartame and, as a letter to the Lancet said in 1999, almost all the adverse reports across many websites are anecdotal. The letter pointed about that while a 330ml can of diet coke would provide 20mg of methanol, the same amount of fruit juice would yield 40mg. The FDA said that aspartame was “one of the most thoroughly tested and studied food additives the agency has ever approved”. The National Cancer Institute in the US says that there is no clear evidence that any of the artificial sweeteners commonly available are associated with an increased risk of cancers in humans.

But these drinks are not good for you. By drinking them you displace those with nutritional value such as milk (essential for healthy bones and teeth) and fruit juice. The UK Food Standards Agency has launched a pilot study to test individual sensitivity to aspartame. In the meantime you should avoid fizzy drinks with sugar because they have nothing to redeem them except their taste, and only drink diet ones on a limited basis.

 

 Dr Dillners health dilemmas: should I give up fizzy drinks? Dr Dillners health dilemmas: should I give up fizzy drinks?

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Fifteen minutes’ exercise a day can boost life expectancy

August 17, 2011

Exercise 007 Fifteen minutes exercise a day can boost life expectancy

Get up fom the sofa and get going on an exercise program that will help reduce overall body fat and lower that cholesterol before you begin having health problems. I am sure you can 15 minutes a day in your busy schedule. Remember before starting any sort of exercise program consult your family physician and start slowly. Take control of your health and the payoff will be a longer enjoyable life with your loved ones.

Pass it on,

Dr Anthony

yepodcom2Logo1 150x150 Fifteen minutes exercise a day can boost life expectancy  


poweredbyguardian Fifteen minutes exercise a day can boost life expectancyThis article titled “Fifteen minutes’ exercise a day can boost life expectancy” was written by Maev Kennedy, for guardian.co.uk on Tuesday 16th August 2011 10.49 UTC

A cheering piece of research suggests that just 15 minutes of exercise a day – half the recommended amount in the UK – can boost life expectancy.

A study in Taiwan, reported in The Lancet, tracked more than 400,000 men and women over 12 years, and showed significant benefits from 15 minutes a day or 90 minutes a week of moderate exercise such as brisk walking. The UK government currently recommends that adults get 150 minutes of exercise a week.

The Taiwanese study found that compared with the inactive group in the study, the exercisers had a three-year longer life expectancy, and reduced their mortality risk by 14%.

Dr Chi-Pang Wen, lead author of the study, told ABC News that 30 minutes a day for five or more days a week remained the golden rule, but half that could still be very beneficial. “Finding a slot of 15 minutes is much easier than finding a 30-minute slot in most days of the week.”

The researchers also found that people who did some exercise tended to get a taste for it and do more – every additional 15 minutes reduced all cause death risks by another 4%.

England’s chief medical officer, Sally Davies, told the BBC the study would remind people there were many ways of getting exercise, “activities like walking at a good pace or digging the garden can count too”.

 Fifteen minutes exercise a day can boost life expectancy Fifteen minutes exercise a day can boost life expectancy

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