" />

Prostate cancer patients given hope by new ‘triple-whammy’ drug

April 1, 2012

blood tests 008 Prostate cancer patients given hope by new triple whammy drug

Good news for prostate cancer patients…especially for those not responding to present day treatments…research has uncovered another potential drug that can be useful in breathing new life in the battle against cancer. With every ground-breaking news …comes hope of a another day to see the sun-rise…keep fighting and never surrender…

That’s my comment…pass it on..

Dr Anthony

http://www.Yepod.com


poweredbyguardianREV Prostate cancer patients given hope by new triple whammy drugThis article titled “Prostate cancer patients given hope by new ‘triple-whammy’ drug” was written by Robin McKie, science editor, for The Observer on Saturday 31st March 2012 23.06 UTC

A new drug that tackles advanced prostate cancer in three different ways has passed its first hurdle towards being approved.

Scientists reported promising early trial results using galeterone, which is designed to treat cancer that no longer responds to hormone therapy. However, researchers counselled caution as tests on the “triple whammy” drug have been carried out on only a small number of patients.

In their tests, scientists based at Harvard University reported that galeterone reduced levels of prostate specific antigen (PSA), a prostate cancer blood marker, by 30% or more in about half of patients. Eleven patients had PSA reductions of 50% or more, and in some there was significant shrinkage in tumour size.

A total of 49 patients took part in the phase one study, which primarily looked at safety and dosing levels. All had “refractory” or “castration resistant” cancer that had ceased to respond to hormone therapy. Currently there is little doctors can do to help prostate cancer patients who progress to this stage.

Galeterone works in three ways: by blocking “receptor” proteins that respond to testosterone; by reducing the number of receptors in tumours; and by targeting an enzyme that is linked to hormone pathways involved in the cancer. Trial leader Dr Mary-Ellen Taplin described the galeterone study as “exciting for those of us in the medical community treating this life-threatening cancer”.

The findings were presented at the annual meeting of the American Association for Cancer Research in Chicago. A larger phase two trial, focusing on the drug’s effectiveness, is planned later this year.

The results were welcomed by Dr Kate Holmes, head of research at the Prostate Cancer Charity. “This very early stage research, conducted among a small group of men, indicates that galeterone shows potential as a new treatment for men with advanced prostate cancer.

“This new drug is in its infancy and full results have yet to be published, meaning that it is simply too soon to tell whether or not this drug is capable of living up to its early promise.

“Men in the final stages of prostate cancer have very few options available to them and we desperately need to increase the number of effective treatments,” she said.

“The researchers have plans to test the drug in a further trial, to fully investigate the full side-effects and safety of treatment. We look forward to reading the full publication of this study in due course, and await with anticipation the results of further trials.”

 Prostate cancer patients given hope by new triple whammy drug

guardian.co.uk © Guardian News & Media Limited 2010

Published via the Guardian News Feed plugin for WordPress.

Takeaway pizzas twice as salty as those from supermarkets, study finds

March 30, 2012

Pizza 008 Takeaway pizzas twice as salty as those from supermarkets, study finds

What? You got to be kidding…right..? The fresher made pizza has more salt! You sit down at your favorite pizza shop and you order a super size pizza for the entire family…and the only thought going through my head is….well at least they are using fresh ingredients….right…I would never imagine that it could have 3 times the amount of salt as supermarket pizza…really? I still don’t believe it!!!   

That’s my comment…pass it on.. 

Dr Anthony

Yepod.com 


poweredbyguardianREV Takeaway pizzas twice as salty as those from supermarkets, study findsThis article titled “Takeaway pizzas twice as salty as those from supermarkets, study finds” was written by Rebecca Smithers, consumer affairs correspondent, for The Guardian on Monday 26th March 2012 06.00 UTC

Takeaway pizzas from chains and fast-food restaurants typically contain up to two and a half times more salt than the equivalent from supermarkets, research from health groups reveals.

Campaigners said consumers were being let down by the absence of clear labelling and information about high levels of salt – which is a major health risk – in takeaway foods.

Half of all the takeaway pizzas surveyed contained the entire maximum daily recommendation of salt – six grams (o.2 oz).

The survey by Consensus Action on Salt and Health and the Association of London Environmental Health Managers is released at the start of the annual Salt Awareness Week.

It analysed 199 margherita and pepperoni fresh and frozen pizzas from takeaways, pizza chains and supermarkets across the UK. They found that takeaway pizzas were found to contain up to two and a half times more salt than the average supermarket pizza (2.73g of salt per 100g compared with 1.08g salt/100g).

A pepperoni pizza from the Adam & Eve restaurant in Mill Hill, London, contained 10.57g of salt. At 2.73g of salt per 100g, it means the food is saltier than Atlantic seawater, which is 2.5g of salt per 100g. The restaurant said it has now changed its recipe to make its pizza less salty.

The Department of Health’s target for salt content in pizza by the end of 2012 is a maximum of 1.25g of salt per 100g. But less than a fifth (16%) of the takeaway pizzas tested met this target compared with three-quarters (72%) of supermarket pizzas.

Prof Graham MacGregor, chairman of Cash and professor of Cardiovascular Medicine at the Wolfson Institute of Preventive Medicine at Barts and the London School of Medicine said: “The government is not taking enough action to reduce the amount of salt in the takeaway sector. Salt puts up our blood pressure – the highest risk factor for stroke. Reducing our intake would save thousands of people suffering and dying from a stroke.”

In supermarkets, more than eight in 10 pizzas (85%) provided some form of front of pack nutrition information. A Pizza Express supermarket pizza had almost half the salt of the takeaway equivalent and less than one in five supermarket pizzas are high in salt although two in three are high in saturated fat.

The saltiest supermarket pizza was Tesco’s Full-on-flavour Simply Pepperoni thin stone-baked pizza which had 1.8g (4.77g per 265g pizza). Tesco said: “We have been cutting levels of salt across our ranges since 2005 and continually look at how we can improve products further. We are in the process of reducing salt in this particular pizza and in just a few weeks it will have 10% less salt.”

 Takeaway pizzas twice as salty as those from supermarkets, study finds

guardian.co.uk © Guardian News & Media Limited 2010

Published via the Guardian News Feed plugin for WordPress.

It’s a twice in a lifetime moment: the transit of Venus across the Sun

March 25, 2012

Transit of Venus in 2004 008 Its a twice in a lifetime moment: the transit of Venus across the Sun

If you are into the stars in the sky….then you will not want to miss the show on June 6…that’s when Venus plans on crossing in front of the sun….so make plans for the entire family to participate in this special time…be part of the historical event…reach for the stars..

That’s my comment…pass it on..

me cartoon 150x150 Its a twice in a lifetime moment: the transit of Venus across the Sun

Dr Anthony

 

http://yepod.com

http://www.yepod.com/?p=40849


poweredbyguardianREV Its a twice in a lifetime moment: the transit of Venus across the SunThis article titled “It’s a twice in a lifetime moment: the transit of Venus across the Sun” was written by Robin McKie, science editor, for The Observer on Sunday 25th March 2012 00.07 UTC

A tiny speck will appear on one side of the Sun in a few weeks and slowly traverse the solar disc for a few hours. The movement of that little black dot may seem insignificant. But it is one of the rarest sights in astronomy, an event known as a transit of Venus. Miss this one and you will have to wait until 2117 for the next.

Earth’s closest planetary neighbour, which is currently in close and spectacular alignment with Jupiter in the night sky, will make its passage across the Sun’s disc on 6 June and can expect to make scientific headlines – for astronomers hope studies of the transit will provide them with key data for studying worlds that orbit distant stars.

“This transit is special because it is the last time in our lifetimes that we will have an opportunity to collect data for a planet as well characterised as Venus,” said David Crisp of Nasa’s Jet Propulsion Laboratory in Pasadena, California. “We will have to make the most of it.”

Venus, for all its glittering beauty in the night sky and its association with the Roman goddess of love, is a deeply unpleasant world. It has a surface temperature of 460C, its dense atmosphere of carbon dioxide has incinerated or crushed all robot spacecraft that have landed on it and its surface is shrouded by thick clouds of sulphuric acid. Once thought to be a sister world to Earth, because of their similar sizes and orbits round the Sun, Venus is more like a vision of hell.

Nevertheless studies of the planet, and its rare transits, have provided scientists with crucial scientific data and June’s event will be no exception. In particular, astronomers will use it to test techniques they are developing to study the atmospheres of exoplanets – worlds that orbit other suns – and to spot those that possess life-supporting gases such as oxygen and water vapour.

“This is an incredibly hard thing to do,” said Dr Suzanne Aigrain of Oxford University. “The light from a star is about a billion times stronger than the light reflected by a planet. So just spotting one in orbit round a star that is many light years away is a considerable achievement. Using that light to analyse a planet’s atmosphere is even harder. Nevertheless, the transit of Venus should help us do that.”

In the past few years, the study of exoplanets has gone through a revolution with the launch of spacecraft such as the US observatory Kepler. Its telescopes spot tiny falls in light emissions of stars that occur when a planet passes in front of it. Just as the transit of Venus causes a slight dimming of the Sun’s light, so an exoplanet reveals its presence when it transits a distant star.

That drop in light provides key data about an exoplanet’s size and orbit. However, scientists want to build orbiting observatories that will study tiny changes in the light of a star as it passes through the atmosphere of an orbiting exoplanet. These changes will allow them to assess the composition of that exoplanet’s atmosphere and make estimates of surface conditions. Does it have a thick crushing atmosphere or does it possess only thin levels of gas and is therefore unlikely to support life? Does it contain oxygen or does it have poisonous gases? And that is where the transit of Venus should provide crucial data, says Crisp.

“We are developing techniques that will allow us to determine how different exoplanet atmospheres will produce changes in the light from the stars they orbit.

“However, we won’t be sure our techniques are right unless we can test them on a planet for which we have precise knowledge – and that, of course, is where Venus comes in. Thanks to probes like Europe’s Venus Express, we have precise knowledge about its atmosphere and surface. By studying Venus as if it was an exoplanet we will know how good are our techniques and how much they need to be refined. A whole network of astronomers will be studying the transit of Venus for this reason.”

A transit of Venus occurs when the planet and Earth, whose paths round the Sun tilt at slightly different angles, line up exactly where their orbits cross. This occurs only four times every 243 years, in pairs separated by eight years. Only six transits of Venus are known to have been observed (though claims are made for earlier observations by Persian astronomers) with the last, in 2004, watched by millions who used telescopes to project images of the Sun’s disc and the dot of Venus on to cards or electronic monitors. After this year’s, the next will be in 2117 and then 2125. When the previous pair occurred, Queen Victoria was on the throne.

The first transit of Venus was predicted by Johannes Kepler who calculated one would occur in 1631. However, this was not visible from Europe. The next one occurred on 4 December 1639 when Jeremiah Horrocks became the first person to watch a transit of Venus when he shone an image of the Sun on to a piece of white card and was rewarded, around 3.15pm, with the sight of the black dot of the planet crawling across the solar disc. From his observations, Horrocks used triangulation techniques to make the best estimate then attempted for the size of Venus and the distance of the Earth from the Sun, though in the latter case he was still out by many millions of miles.

The next pair of transits – 1761 and 1769 – got a lot more attention. Expeditions were sent across the globe, including Captain James Cook’s first expedition. He visited Tahiti to observe the transit, from a place that is still known as Point Venus. The aim of these various voyages was to collect as many readings as possible from different parts of the world to calculate the size of the solar system with precision.

The expeditions pushed science and many scientists to the limit, the unluckiest being the French astronomer Guillaume Le Gentil, who set out from Paris in March 1760 but was still at sea on transit day, 6 June 1761. The rolling of his ship prevented him from taking observations. So Le Gentil decided to wait for the next transit in 1769 and built a small observatory in Pondicherry, a French colony in India, where he waited patiently for the next transit on 4 June 1769.

On the day, clouds filled the sky even though it had been clear every morning for the preceding month. Le Gentil saw nothing. On his journey home, he contracted dysentery and was caught in a storm that delayed his return to Paris until October 1771 where he found he had been declared legally dead, his wife had remarried and all his relatives had enthusiastically plundered his estate. He eventually remarried, however, and enjoyed an apparently happy life for another 21 years.

Using the observations from the 1761 and 1769 transits, the distance from the Earth to the Sun was estimated as being 153m km. The correct figure, of 149.59m km, was not achieved until results of the transits of 1874 and 1882 were obtained. Today, a Venus transit is of little direct use to astronomers; it is its usefulness in testing transit techniques that now excites scientists.

They are also intriguing events. In 2004, the entire transit was seen in Britain and watched by millions. This time we will catch only a glimpse, with the best observing conditions occurring in Australia, Japan and south-east Asia. In Britain, it will only be possible to watch the last moments of the transit as the sun rises. After that, there will be a lull of 105 years.

Additional research by Mia de Graaf

 Its a twice in a lifetime moment: the transit of Venus across the Sun

guardian.co.uk © Guardian News & Media Limited 2010

Published via the Guardian News Feed plugin for WordPress.

Categories

Tags

RSS Your Educational Podcast & Video

Links

  • Dr Anthony's English as a Second Language

© 2009-2012 Your Educational Podcast and Video All Rights Reserved